Although DHEA supplementation increases androgens, these small increases may only prompt zero-to-small changes to muscle size and strength: a 2018 systematic review of randomized controlled trials (RCTs) concluded that supplementation with DHEA had no effects on muscle size or strength,[1] and a 2020 meta-analysis of RCTs found small benefits (often at doses 50–100 mg) to body composition: increased lean body mass (0.99 lbs) and decreased fat mass (-1%).[2]
References
- ^Beaudart C, Rabenda V, Simmons M, Geerinck A, Araujo De Carvalho I, Reginster JY, Amuthavalli Thiyagarajan J, Bruyère OEffects of Protein, Essential Amino Acids, B-Hydroxy B-Methylbutyrate, Creatine, Dehydroepiandrosterone and Fatty Acid Supplementation on Muscle Mass, Muscle Strength and Physical Performance in Older People Aged 60 Years and Over. A Systematic Review on the Literature.J Nutr Health Aging.(2018)
- ^Wang F, He Y, O Santos H, Sathian B, C Price J, Diao JThe effects of dehydroepiandrosterone (DHEA) supplementation on body composition and blood pressure: A meta-analysis of randomized clinical trials.Steroids.(2020-Nov)