The evidence for DHEA and fertility outcomes is inconsistent. It might help outcomes in women with poor ovarian response undergoing in vitro fertilization (IVF),[1][2] but one meta-analysis of randomized controlled trials in women with poor/diminished ovarian response found that while DHEA supplementation increased follicle count, ultimately there was no significant improvement in live birth rates.[3]
References
- ^Wang J, Liu B, Wen J, Qu BThe Role of Dehydroepiandrosterone in Improving Fertilization Outcome in Patients with DOR/POR: A Systematic Review and Meta- Analysis.Comb Chem High Throughput Screen.(2023)
- ^Yuan WS, Abu MA, Ahmad MF, Elias MH, Abdul Karim AKEffects of Dehydroepiandrosterone (DHEA) Supplementation on Ovarian Cumulus Cells following In Vitro Fertilization (IVF)/Intra-Cytoplasmic Sperm Injection (ICSI) Treatment-A Systematic Review.Life (Basel).(2023-May-24)
- ^Zhang J, Jia H, Diao F, Ma X, Liu J, Cui YEfficacy of dehydroepiandrosterone priming in women with poor ovarian response undergoing IVF/ICSI: a meta-analysis.Front Endocrinol (Lausanne).(2023)