Ecklonia Cava

Last Updated: September 28 2022

Ecklonia Cava is a brown seaweed with a rich polyphenolic content (this particular subset being known as eckols or phlorotannins) that confers anti-oxidant properties, it is being investigated for health properties.

Ecklonia Cava is most often used for

Summary

Ecklonia Cava is a type of seaweed which is known to be one of the highest sources of phloroglucinols, a type of antioxidant compound that appears to be unique to sea plants. The phloroglucinols appear to be very potent anti-oxidants, and these benefits have been noted after oral ingestion as well.

That being said, the potency of phloroglucinols being anti-oxidants seems to be a bit separate from the magnitude of benefit one gets from ingesting these compounds. Benefits have been noted on blood pressure, blood glucose, and inflammation but for the most part these are statistically sound but practically small benefits. The current human evidence is unconvincing for the most part, although these compounds and seaweed are undoubtedly "healthy" as a general statement.

Other effects that seem interesting for Ecklonia Cava are an apparently anti-allergic potential that is not highly explored, and there appears to be some anti-cancer properties as well (mostly tested in regards to melanoma). Topical application of Ecklonia is one of a few compounds that can enhance hair growth, and it appears to be novel in the sense that it both inhibits androgen-induced hair loss and also directly enhances hair growth (so it, by itself, appears to be some form of combination therapy).

What else is Ecklonia Cava known as?
Ecklonia Cava should not be confused with:
  • Kava (not related to Ecklonia Cava)
Dosage information

Ecklonia Cava products appear to benefit the body in relatively low doses, with weak health benefits on blood pressure and glucose in the range of 100mg; higher doses (which would be expected when consuming the seaweed itself as a food product) confer dose-dependent responses.

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      References
      1.^Ahn G, Park E, Lee WW, Hyun JW, Lee KW, Shin T, Jeon YJ, Jee YEnzymatic extract from Ecklonia cava induces the activation of lymphocytes by IL-2 production through the classical NF-κB pathwayMar Biotechnol (NY).(2011 Feb)
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      15.^Kang IJ, Jeon YE, Yin XF, Nam JS, You SG, Hong MS, Jang BG, Kim MJButanol extract of Ecklonia cava prevents production and aggregation of beta-amyloid, and reduces beta-amyloid mediated neuronal deathFood Chem Toxicol.(2011 Sep)
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      42.^Kang KA, Lee KH, Park JW, Lee NH, Na HK, Surh YJ, You HJ, Chung MH, Hyun JWTriphlorethol-A induces heme oxygenase-1 via activation of ERK and NF-E2 related factor 2 transcription factorFEBS Lett.(2007 May 15)
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      52.^Kim MM, Ta QV, Mendis E, Rajapakse N, Jung WK, Byun HG, Jeon YJ, Kim SKPhlorotannins in Ecklonia cava extract inhibit matrix metalloproteinase activityLife Sci.(2006 Sep 5)
      55.^Heo SJ, Ko SC, Cha SH, Kang DH, Park HS, Choi YU, Kim D, Jung WK, Jeon YJEffect of phlorotannins isolated from Ecklonia cava on melanogenesis and their protective effect against photo-oxidative stress induced by UV-B radiationToxicol In Vitro.(2009 Sep)
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      60.^Kang JI, Kim SC, Kim MK, Boo HJ, Jeon YJ, Koh YS, Yoo ES, Kang SM, Kang HKEffect of Dieckol, a Component of Ecklonia cava, on the Promotion of Hair GrowthInt J Mol Sci.(2012)
      65.^Kang SM, Heo SJ, Kim KN, Lee SH, Yang HM, Kim AD, Jeon YJMolecular docking studies of a phlorotannin, dieckol isolated from Ecklonia cava with tyrosinase inhibitory activityBioorg Med Chem.(2012 Jan 1)