Horse Chestnut

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    Last Updated: June 12, 2025

    Horse chestnut (Aesculus hippocastanum) extract is a traditional botanical remedy derived from the seeds of a tree native to the Balkan peninsula. Its primary active compound, aescin, has been extensively studied for its beneficial effects on the circulatory system.

    Overview

    Dosage information

    Formulation:

    Horse chestnut is commonly available as a standardized seed extract in the form of capsules, tablets, topical creams/gels, and liquid extracts. Most of the evidence supports using oral capsule formulations containing 16% to 20% of aescin (its main active ingredient).

    Range of dosages studied:

    50 to 150 mg

    Examine Database: Horse Chestnut

    Frequently asked questions

    Update History

    Research Breakdown

    Examine Database References

    1. Leg Edema - Diehm C, Trampisch HJ, Lange S, Schmidt CComparison of leg compression stocking and oral horse-chestnut seed extract therapy in patients with chronic venous insufficiencyLancet.(1996 Feb 3)
    2. Leg Edema - Rainer KochComparative study of Venostasin and Pycnogenol in chronic venous insufficiencyPhytother Res.(2002 Mar)
    3. Leg Edema - Pittler MH, Ernst EHorse chestnut seed extract for chronic venous insufficiencyCochrane Database Syst Rev.(2006 Jan 25)
    4. Hemorrhoids Symptoms - Pirard J, Gillet P, Guffens JM, Defrance PDouble blind study of reparil in proctologyRev Med Liege.(1976 May 15)