Most trials looking at the effects of Mucuna pruriens on symptoms of Parkinson's disease or male infertility have used daily doses ranging between 5 and 45 grams of adequately prepared seed powder, corresponding to approximately 200 mg to 1,500 mg of L-DOPA.

Preparations of Mucuna pruriens, which contain L-DOPA, may be 2–3 times more potent than an equivalent dose of isolated L-DOPA (when not combined with carbidopa). Mucuna pruriens should not be used in conjunction with medications containing L-DOPA; combining the two could potentially result in excessively high dopamine levels, leading to adverse effects. Also, the potential blood-glucose-lowering properties of Mucuna pruriens mean that it could interact with diabetes medications.