Overview
What is St. John’s wort?
What are the main benefits of St. John’s wort?
What are the main drawbacks of St. John’s wort?
How does St. John’s wort work?
Dosage information
The most common dosage of St. John's wort extract found in studies is 300mg, taken up to three times a day (for a total of 900 mg).[1]
Safety InformationNew
Examine Database: St. John's Wort
Research FeedRead all studies
In this 4-week randomized controlled trial in 48 adults who lived in nursing facilities and had pressure ulcers, topical application of St. John’s wort oil did not improve wound healing in comparison with usual care.
Frequently asked questions
Does St. John’s wort interact with any other medication?
Can St. John’s wort interact with other supplements?
Is St. John’s wort safe during pregnancy?
Is St. John’s wort safe during breastfeeding?
Does St. John’s wort have other mechanisms of action?
Update History
Safety Information added
Full FAQ and database update
References
Examine Database References
- Depression Symptoms - Linde K, Berner MM, Kriston LSt John's wort for major depression.Cochrane Database Syst Rev.(2008-Oct-08)
- Depression Symptoms - Linde K, Berner M, Egger M, Mulrow CSt John's wort for depression: meta-analysis of randomised controlled trials.Br J Psychiatry.(2005-Feb)
- Depression Symptoms - Cui YH, Zheng YA meta-analysis on the efficacy and safety of St John's wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults.Neuropsychiatr Dis Treat.(2016)








