Stinging Nettle
•Last Updated: September 28 2022
Stinging Nettle is quite a nasty plant to touch, but oral ingestion of pills without spikes results in a moderately potent anti-inflammatory that can reduce the sniffles. Does not boost testosterone despite being claims to, although it can help Benign Prostatic Hyperplasia and urine abnormalities.
Stinging Nettle is most often used for
Last Updated: September 28 2022
Note that Stinging Nettle is also known as:
- Urtica dioica
- Radix Urticae
- Common Nettle
- Greater Nettle
- Ortica
- Tsuknida
120mg of Stinging Nettle (root) taken three times a day (totalling 360mg) is associated with benefit in Benign Prostate Hyperplasia.
For allergies, the studied dosage is 300 mg twice a day of freeze-dried nettle leaf.
The evidence is much better for nettle root and prostatic enlargement than for nettle leaf and allergies.
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2.^Nahata A, Dixit VKAmeliorative effects of stinging nettle (Urtica dioica) on testosterone-induced prostatic hyperplasia in ratsAndrologia.(2012 May)
3.^Schöttner M, Gansser D, Spiteller GLignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG)Planta Med.(1997 Dec)
4.^Schöttner M, Spiteller G, Gansser DLignans interfering with 5 alpha-dihydrotestosterone binding to human sex hormone-binding globulinJ Nat Prod.(1998 Jan)
8.^Otles S, Yalcin BPhenolic compounds analysis of root, stalk, and leaves of nettleScientificWorldJournal.(2012)
9.^Determination of some phenolic compounds in flax seed and nettle roots by HPLC with coulometric electrode array detection.()
10.^Fiamegos YC, Nanos CG, Vervoort J, Stalikas CDAnalytical procedure for the in-vial derivatization--extraction of phenolic acids and flavonoids in methanolic and aqueous plant extracts followed by gas chromatography with mass-selective detectionJ Chromatogr A.(2004 Jul 2)
11.^Analysis of flavonoids and phenolic acids in Greek aromatic plants: Investigation of their antioxidant capacity and antimicrobial activity.()
15.^Safarinejad MRUrtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover studyJ Herb Pharmacother.(2005)
16.^Gansser D, Spiteller GPlant constituents interfering with human sex hormone-binding globulin. Evaluation of a test method and its application to Urtica dioica root extractsZ Naturforsch C.(1995 Jan-Feb)
17.^Schmidt KEffect of radix urticae extract and its several secondary extracts on blood SHBG in benign prostate hyperplasiaFortschr Med.(1983 Apr 21)
18.^Hryb DJ, Khan MS, Romas NA, Rosner WThe effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranesPlanta Med.(1995 Feb)
19.^Lopatkin NA, Sivkov AV, Medvedev AA, Walter K, Schlefke S, Avdeĭchuk IuI, Golubev GV, Mel'nik KP, Elenberger NA, Engelman UCombined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trialUrologiia.(2006 Mar-Apr)
20.^Lopatkin N, Sivkov A, Walther C, Schläfke S, Medvedev A, Avdeichuk J, Golubev G, Melnik K, Elenberger N, Engelmann ULong-term efficacy and safety of a combination of sabal and urtica extract for lower urinary tract symptoms--a placebo-controlled, double-blind, multicenter trialWorld J Urol.(2005 Jun)
21.^Bondarenko B, Walther C, Funk P, Schläfke S, Engelmann ULong-term efficacy and safety of PRO 160/120 (a combination of sabal and urtica extract) in patients with lower urinary tract symptoms (LUTS)Phytomedicine.(2003)
22.^Bercovich E, Saccomanni MAnalysis of the results obtained with a new phytotherapeutic association for LUTS versus control. (corrected)Urologia.(2010 Jul-Sep)
23.^Lopatkin N, Sivkov A, Schläfke S, Funk P, Medvedev A, Engelmann UEfficacy and safety of a combination of Sabal and Urtica extract in lower urinary tract symptoms--long-term follow-up of a placebo-controlled, double-blind, multicenter trialInt Urol Nephrol.(2007)
25.^Hirano T, Homma M, Oka KEffects of stinging nettle root extracts and their steroidal components on the Na+,K(+)-ATPase of the benign prostatic hyperplasiaPlanta Med.(1994 Feb)
26.^Roschek B Jr, Fink RC, McMichael M, Alberte RSNettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitisPhytother Res.(2009 Jul)
27.^Randall C, Meethan K, Randall H, Dobbs FNettle sting of Urtica dioica for joint pain--an exploratory study of this complementary therapyComplement Ther Med.(1999 Sep)
28.^Randall C, Randall H, Dobbs F, Hutton C, Sanders HRandomized controlled trial of nettle sting for treatment of base-of-thumb painJ R Soc Med.(2000 Jun)
29.^Randall C, Dickens A, White A, Sanders H, Fox M, Campbell JNettle sting for chronic knee pain: a randomised controlled pilot studyComplement Ther Med.(2008 Apr)
30.^Rayburn K, Fleischbein E, Song J, Allen B, Kundert M, Leiter C, Bush TStinging nettle cream for osteoarthritisAltern Ther Health Med.(2009 Jul-Aug)
31.^Jacquet A, Girodet PO, Pariente A, Forest K, Mallet L, Moore NPhytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trialArthritis Res Ther.(2009)
32.^Namazi N, Esfanjani AT, Heshmati J, Bahrami AThe effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes: a randomized double-blind control trialPak J Biol Sci.(2011 Aug 1)
33.^Teucher T, Obertreis B, Ruttkowski T, Schmitz HCytokine secretion in whole blood of healthy subjects following oral administration of Urtica dioica L. plant extractArzneimittelforschung.(1996 Sep)
36.^Bielory LComplementary and alternative interventions in asthma, allergy, and immunologyAnn Allergy Asthma Immunol.(2004 Aug)
37.^Mittman PRandomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitisPlanta Med.(1990 Feb)
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