Sulbutiamine is a synthetic molecule which consists of two Thiamine (Vitamin B1) molecules bound together by a sulfur group, and appears to be somewhat useful in alleviating fatigue; especially that associated with infection.
Human studies using sulbutiamine supplementation have used 400mg daily. It is not clear if this is near the optimal dosage, and an ideal dosing regimen (with or without meals and how many divided doses a day) is not currently known.
Sulbutiamine is most often used for Energy & Fatigue. The Examine Database covers Type 2 Diabetes and Diabetic Neuropathy.
