Vanadium

Last Updated: September 28 2022

Vanadium is a mineral that is not one of the Essential Mineral compounds, but is sometimes ingested in the diet. Can be found in bone tissues, Vanadium may influence glucose metabolism in an anti-diabetic manner.

Vanadium is most often used for

Dosage information

The majority of research on vanadium uses an oral dose of 100mg as a once daily supplement in persons with poor glucose tolerance. It is unsure if this is the optimal dose, but it appears to be effective.

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      References
      4.^Kadota S, Fantus IG, Deragon G, Guyda HJ, Hersh B, Posner BIPeroxide(s) of vanadium: a novel and potent insulin-mimetic agent which activates the insulin receptor kinaseBiochem Biophys Res Commun.(1987 Aug 31)
      6.^Cantley LC Jr, Josephson L, Warner R, Yanagisawa M, Lechene C, Guidotti GVanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscleJ Biol Chem.(1977 Nov 10)
      8.^Swarup G, Cohen S, Garbers DLInhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadateBiochem Biophys Res Commun.(1982 Aug)
      10.^Jackson TK, Salhanick AI, Sparks JD, Sparks CE, Bolognino M, Amatruda JMInsulin-mimetic effects of vanadate in primary cultures of rat hepatocytesDiabetes.(1988 Sep)
      12.^Solow BT, Harada S, Goldstein BJ, Smith JA, White MF, Jarett LDifferential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteinsMol Endocrinol.(1999 Oct)
      14.^Haruta T, Uno T, Kawahara J, Takano A, Egawa K, Sharma PM, Olefsky JM, Kobayashi MA rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1Mol Endocrinol.(2000 Jun)
      15.^Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MFPhosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin actionJ Biol Chem.(2002 Jan 11)
      16.^Rice KM, Turnbow MA, Garner CWInsulin stimulates the degradation of IRS-1 in 3T3-L1 adipocytesBiochem Biophys Res Commun.(1993 Feb 15)
      19.^Halberstam M, Cohen N, Shlimovich P, Rossetti L, Shamoon HOral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjectsDiabetes.(1996 May)
      20.^Jacques-Camarena O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF, Medina-Santillán REffect of vanadium on insulin sensitivity in patients with impaired glucose toleranceAnn Nutr Metab.(2008)
      21.^Cohen N, Halberstam M, Shlimovich P, Chang CJ, Shamoon H, Rossetti LOral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitusJ Clin Invest.(1995 Jun)