Thiamine (Vitamin B1)

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    Last Updated: August 28, 2025

    Thiamine (Vitamin B1) is an essential vitamin involved heavily in glucose production. While not a common deficiency in an otherwise healthy diet and limited benefits when taken by a healthy subject, instances of high blood glucose and/or alcoholism can increase the need for this vitamin drastically.

    Dosage information

    Thiamine supplements are usually taken at doses well above the RDA, such as 100-300mg, in instances where thiamine is considered to be deficient such as high blood sugar or high alcohol intake. When using thiamine at this dose timing does not matter much and either one dose can be taken in the morning or multiple doses throughout; thiamine does not need to be ingested with food to be absorbed.

    Examine Database: Thiamine (Vitamin B1)

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    Research Breakdown

    Examine Database References

    1. High-density lipoprotein (HDL) - Alaei-Shahmiri F, Soares MJ, Zhao Y, Sherriff JThe impact of thiamine supplementation on blood pressure, serum lipids and C-reactive protein in individuals with hyperglycemia: a randomised, double-blind cross-over trialDiabetes Metab Syndr.(2015 Oct-Dec)
    2. PMS Symptoms - Abdollahifard S, Rahmanian Koshkaki A, Moazamiyanfar RThe effects of vitamin B1 on ameliorating the premenstrual syndrome symptomsGlob J Health Sci.(2014 Jul 29)
    3. PMS Symptoms - Samieipour S, et al.EFFECT OF CALCIUM AND VITAMIN B1 ON THE SEVERITY OF PREMENSTRUAL SYNDROME: A RANDOMIZED CONTROL TRIALInt J Pharm Tech.()
    4. Left Ventricular Ejection Fraction - He S, Wang S, Xu T, Wang S, Qi M, Chen Q, Lin L, Wu H, Gan PRole of Thiamine Supplementation in the Treatment of Chronic Heart Failure: An Updated Meta-Analysis of Randomized Controlled Trials.Clin Cardiol.(2024 Jul 1)