What are vitamin C’s main benefits?

    Last Updated: October 25, 2023

    People often supplement with vitamin C when they have a cold. According to various studies, vitamin C may be effective in reducing the duration of a cold, but does not seem to reduce the frequency of colds in a population.[1][2] The available literature suggests that a dose ranging from 200 mg to 2,000 mg could be beneficial for reducing cold duration.

    Often utilized for its antioxidant effects, vitamin C has been studied for its potential role in Alzheimer’s disease and cancer. Lower vitamin C levels are present in people with Alzheimer’s, even with adequate dietary intake.[3] It is thought that oxidative stress plays a major role in the pathogenesis of the disease, so vitamin C’s antioxidative effects could be beneficial.[4][5] In rodent studies, oral vitamin C was able to reduce oxidative and inflammatory biomarkers.[6] In recent cancer research, vitamin C was found to promote oxidative stress in cancer cells, leading to cytotoxic effects at high doses in mice.[7] While promising, further research and human studies are required to determine efficacy.

    References

    1. ^Hemilä H, Chalker EVitamin C for preventing and treating the common coldCochrane Database Syst Rev.(2013 Jan 31)
    2. ^Anderson TW, Suranyi G, Beaton GHThe effect on winter illness of large doses of vitamin C.Can Med Assoc J.(1974-Jul-06)
    3. ^Rivière S, Birlouez-Aragon I, Nourhashémi F, Vellas BLow plasma vitamin C in Alzheimer patients despite an adequate diet.Int J Geriatr Psychiatry.(1998-Nov)
    4. ^Christen YOxidative stress and Alzheimer disease.Am J Clin Nutr.(2000-Feb)
    5. ^Heo JH, Hyon-Lee , Lee KMThe possible role of antioxidant vitamin C in Alzheimer's disease treatment and prevention.Am J Alzheimers Dis Other Demen.(2013-Mar)
    6. ^Rosales-Corral S, Tan DX, Reiter RJ, Valdivia-Velázquez M, Martínez-Barboza G, Acosta-Martínez JP, Ortiz GGOrally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-beta peptide in rat brain: a comparative, in vivo study versus vitamin C and E.J Pineal Res.(2003-Sep)
    7. ^Chen Q, Espey MG, Sun AY, Pooput C, Kirk KL, Krishna MC, Khosh DB, Drisko J, Levine MPharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in miceProc Natl Acad Sci U S A.(2008 Aug 12)