Zinc deficiency is common in people with human immunodeficiency virus (HIV)[1][2] and is associated with disease progression.[3][2] Accordingly, some studies show that supplementation with zinc may delay immunological failure and reduce the occurrence of opportunistic infections in participants with both zinc deficiency and HIV.[4][5][6]
References
- ^Clara Y Jones, Alice M Tang, Janet E Forrester, Jinyong Huang, Kristy M Hendricks, Tamsin A Knox, Donna Spiegelman, Richard D Semba, Margo N WoodsMicronutrient levels and HIV disease status in HIV-infected patients on highly active antiretroviral therapy in the Nutrition for Healthy Living cohortJ Acquir Immune Defic Syndr.(2006 Dec 1)
- ^Baum MK, Campa A, Lai S, Lai H, Page JBZinc status in human immunodeficiency virus type 1 infection and illicit drug use.Clin Infect Dis.(2003)
- ^N M Graham, D Sorensen, N Odaka, R Brookmeyer, D Chan, W C Willett, J S Morris, A J SaahRelationship of serum copper and zinc levels to HIV-1 seropositivity and progression to AIDSJ Acquir Immune Defic Syndr (1988).(1991)
- ^Baum MK, Lai S, Sales S, Page JB, Campa ARandomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults.Clin Infect Dis.(2010-Jun-15)
- ^Mocchegiani E, Veccia S, Ancarani F, Scalise G, Fabris NBenefit of oral zinc supplementation as an adjunct to zidovudine (AZT) therapy against opportunistic infections in AIDS.Int J Immunopharmacol.(1995-Sep)
- ^Zeng L, Zhang LEfficacy and safety of zinc supplementation for adults, children and pregnant women with HIV infection: systematic review.Trop Med Int Health.(2011-Dec)