Which supplements are of most interest for fat loss?

Supplements of interest for fat loss typically either increase total daily energy expenditure, suppress appetite, or increase the rate at which fatty acids are released from fat cells. The following are some of the most popular supplements related to fat loss:

• Caffeine
• Ephedrine
• Green tea catechins
• Green coffee extract
• Yohimbine
• Capsaicin
• Garcinia cambogia
• Conjugated linoleic acid

Most supplements sold for fat loss are ineffective or there’s not enough evidence in humans to support their efficacy, and some can even be harmful. For example, yohimbine, ephedrine, and caffeine can all induce anxiety in some people.