Infantile Colic

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    Last Updated: August 22, 2023

    “Infantile colic” is characterized by repeated episodes of intense/frequent crying or discontent with an unknown cause. Caregivers need to be reassured that they are often doing nothing wrong, and that colic usually resolves by itself within 3–4 months. However, supplementation with certain probiotics may help.

    71 references on this page
    2,658 participants in 6 trials and 1 meta-analysis

    Overview

    Examine Database: Infantile Colic

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    Examine Database References

    1. Infant crying - Francesco Savino, Emanuela Pelle, Elisabetta Palumeri, Roberto Oggero, Roberto MinieroLactobacillus reuteri (American Type Culture Collection Strain 55730) versus simethicone in the treatment of infantile colic: a prospective randomized studyPediatrics.(2007 Jan)
    2. Infant crying - Sung V, Hiscock H, Tang ML, Mensah FK, Nation ML, Satzke C, Heine RG, Stock A, Barr RG, Wake MTreating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trialBMJ.(2014 Apr 1)
    3. Infant crying - Savino F, Cordisco L, Tarasco V, Palumeri E, Calabrese R, Oggero R, Roos S, Matteuzzi DLactobacillus reuteri DSM 17938 in infantile colic: a randomized, double-blind, placebo-controlled trialPediatrics.(2010 Sep)
    4. Infant crying - Roos S, Dicksved J, Tarasco V, Locatelli E, Ricceri F, Grandin U, Savino F454 pyrosequencing analysis on faecal samples from a randomized DBPC trial of colicky infants treated with Lactobacillus reuteri DSM 17938PLoS One.(2013)
    5. Infant crying - Sung V, Collett S, de Gooyer T, Hiscock H, Tang M, Wake MProbiotics to prevent or treat excessive infant crying: systematic review and meta-analysisJAMA Pediatr.(2013 Dec)
    6. Infant crying - Szajewska H, Gyrczuk E, Horvath ALactobacillus reuteri DSM 17938 for the management of infantile colic in breastfed infants: a randomized, double-blind, placebo-controlled trialJ Pediatr.(2013 Feb)
    7. Infant crying - Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, Corvaglia L, Ballardini E, Bisceglia M, Cinquetti M, Brazzoduro E, Del Vecchio A, Tafuri S, Francavilla RProphylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trialJAMA Pediatr.(2014 Mar)