References
- ^Zhang X, Zhao H, Man J, Yin X, Zhang T, Yang X, Lu MInvestigating Causal Associations of Diet-Derived Circulating Antioxidants with the Risk of Digestive System Cancers: A Mendelian Randomization Study.Nutrients.(2022-Aug-08)
The exact cause of CRC is unknown, but it likely results from an interaction between lifestyle and genetic factors that causes unregulated intestinal cell division. When the process of cell division isn’t controlled properly, the cells can form a tumor. Some evidence suggests that oxidative stress damages cellular DNA, proteins, and lipids, causing mutations that lead to unregulated growth.[1] Finally, Lynch syndrome is an inheritable genetic mutation that significantly increases the risk of developing CRC.