Hashimoto's disease falls under the Autoimmune Disease category.

Evidence-based

Hashimoto's disease

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Rob Stenstrom, Natalka Roshak

•Last Updated: November 20, 2025

Hashimoto’s disease, also known as Hashimoto’s thyroiditis or chronic lymphocytic thyroiditis, is an autoimmune thyroid disorder. It is the most common cause of hypothyroidism in developed countries.

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Last Updated:November 20, 2025

18 references on this page

1,977 participants in 3 trials and 1 meta-analysis

Examine Evidence Grades

BSubjective Well-Being + 1 more

Overview

What is Hashimoto's disease?

What are the main signs and symptoms of Hashimoto's disease?

How is Hashimoto's disease diagnosed?

What are some of the main medical treatments for Hashimoto's disease?

Have any supplements been studied for Hashimoto's disease?

How could diet affect Hashimoto's disease?

Are there any other treatments for Hashimoto's disease?

What causes Hashimoto's disease?

Examine Database: Hashimoto's disease

Autoimmune Protocol (AIP) Diet

9 outcomes

2 outcomes

8 outcomes

5 outcomes

Autoimmune Protocol (AIP) Diet

Research FeedRead all studies

Further research is needed to determine whether curcumin is beneficial for Hashimoto’s disease

In this 12-week randomized controlled trial in 57 participants with Hashimoto’s disease, curcumin reduced (improved) antithyroid antibody levels compared to a placebo, but levels of thyroid-stimulating hormone and T3 and T4 did not differ between the groups.

Selenium for thyroid autoimmunity during pregnancy

Vitamin D supplementation alters T-cell populations in Hashimoto’s

Hashimoto’s thyroiditis and vitamin D

Selenium supplementation in Hashimoto’s thyroiditis

Frequently Asked Questions

What is the difference between Graves’ disease and Hashimoto’s disease?

Which is more dangerous? Graves’ disease or Hashimoto’s disease?

References

Examine Database References

Thyrotropin Releasing Hormone - Chow CC, Phillips DI, Lazarus JH, Parkes ABEffect of low dose iodide supplementation on thyroid function in potentially susceptible subjects: are dietary iodide levels in Britain acceptableClin Endocrinol (Oxf).(1991 May)
Serum T4 - Robert D Abbott, Adam Sadowski, Angela G AltEfficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto's ThyroiditisCureus.(2019 Apr 27)
Serum T4 - Zhang H, Yang Y, Liu S, Yang Y, Liu ZClinical efficacy of selenium supplementation in patients with Hashimoto thyroiditis: A systematic review and meta-analysis.Medicine (Baltimore).(2025 Aug 29)
Weight - Salvatore Benvenga, Antonino Amato, Menotti Calvani, Francesco TrimarchiEffects of carnitine on thyroid hormone actionAnn N Y Acad Sci.(2004 Nov)