Have any supplements been studied for hemorrhoids?

    Last Updated: October 25, 2023

    Fiber supplementation helps to soften stool and reduce constipation, which can minimize irritation to the anal cushions and improve healing. A meta-analysis of controlled trials found that fiber supplementation, most often psyllium, reduced the risk of overall hemorrhoid symptoms by half and was particularly effective for reducing the risk of bleeding. However, it can take up to 6 weeks for these benefits to take effect. Once hemorrhoids have healed, fiber supplementation can be continued as a preventative measure.[1]

    Bioflavonoid supplementation, particularly micronized purified flavonoid fraction (MPFF) containing 90% diosmin and 10% hesperidin, was assessed in two recent meta-analyses of controlled trials. One meta-analysis reported a reduction in bleeding, anal leakage, and overall symptoms, while the other only found an effect for reduced bleeding.[2][3] MPFF is thought to work by reducing vein inflammation and increasing vein tone (the tightness of the vein).[2] While these products are commonly used in other parts of the world, they are not currently approved by the U.S. Food and Drug Administration for hemorrhoid treatment.[4]

    References

    1. ^Alonso-Coello P, Guyatt G, Heels-Ansdell D, Johanson JF, Lopez-Yarto M, Mills E, Zhou QLaxatives for the treatment of hemorrhoids.Cochrane Database Syst Rev.(2005-Oct-19)
    2. ^Sheikh P, Lohsiriwat V, Shelygin YMicronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis.Adv Ther.(2020-Jun)
    3. ^Aziz Z, Huin WK, Badrul Hisham MD, Tang WL, Yaacob SEfficacy and tolerability of micronized purified flavonoid fractions (MPFF) for haemorrhoids: A systematic review and meta-analysis.Complement Ther Med.(2018-Aug)
    4. ^Mott T, Latimer K, Edwards CHemorrhoids: Diagnosis and Treatment Options.Am Fam Physician.(2018-Feb-01)