Have any supplements been studied for mild cognitive impairment?

    Last Updated: October 25, 2023

    The effects of several supplements have been studied in people with mild cognitive impairment. These include omega-3 fatty acids, probiotics, ginkgo biloba, B vitamins, vitamin C, vitamin D, vitamin E, etc. However, the current evidence does not support the use of any supplement in people with mild cognitive impairment for improving cognitive function or preventing dementia.[1][2][3][4] That said, the current evidence is limited, and more high-quality large-scale randomized controlled trials are needed to make definitive conclusions.

    References

    1. ^McCleery J, Abraham RP, Denton DA, Rutjes AW, Chong LY, Al-Assaf AS, Griffith DJ, Rafeeq S, Yaman H, Malik MA, Di Nisio M, Martínez G, Vernooij RW, Tabet NVitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment.Cochrane Database Syst Rev.(2018-11-01)
    2. ^Butler M, Nelson VA, Davila H, Ratner E, Fink HA, Hemmy LS, McCarten JR, Barclay TR, Brasure M, Kane RLOver-the-Counter Supplement Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: A Systematic Review.Ann Intern Med.(2018-Jan-02)
    3. ^Xurui Li, Chang Lv, Jinxiao Song, Jianguo LiEffect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-AnalysisFront Nutr.(2021 Dec 8)
    4. ^Emma Sydenham, Alan D Dangour, Wee-Shiong LimOmega 3 fatty acid for the prevention of cognitive decline and dementiaCochrane Database Syst Rev.(2012 Jun 13)