Nonalcoholic Steatohepatitis (NASH)

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    Louie Neri

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    Marina Shkayeva, Shyam Jayaraman
    Last Updated: October 13, 2024

    Nonalcoholic steatohepatitis (NASH) is a condition where fat buildup in the liver leads to liver inflammation and damage. Progression of NASH can cause liver hardening (fibrosis) and scarring (cirrhosis).

    11 references on this page
    3,751 participants in 11 trials and 5 meta-analyses

    Overview

    Examine Database: Nonalcoholic Steatohepatitis (NASH)

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    Frequently asked questions

    Examine Database References

    1. Ghrelin - Gonciarz M, Bielański W, Partyka R, Brzozowski T, Konturek PC, Eszyk J, Celiński K, Reiter RJ, Konturek SJPlasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatoninJ Pineal Res.(2012 Jun 13)
    2. Liver Enzymes - Chitapanarux T, Tienboon P, Pojchamarnwiputh S, Leelarungrayub DOpen-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patientsJ Gastroenterol Hepatol.(2009 Jun)
    3. Liver Enzymes - T Hasegawa, M Yoneda, K Nakamura, I Makino, A TeranoPlasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot studyAliment Pharmacol Ther.(2001 Oct)
    4. Liver Enzymes - Sumida Y, Naito Y, Tanaka S, Sakai K, Inada Y, Taketani H, Kanemasa K, Yasui K, Itoh Y, Okanoue T, Yoshikawa TLong-term (>=2 yr) efficacy of vitamin E for non-alcoholic steatohepatitisHepatogastroenterology.(2013 Sep)
    5. Liver Enzymes - Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, NASH CRNPioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitisN Engl J Med.(2010 May 6)
    6. Liver Enzymes - Miwa Kawanaka, Sabina Mahmood, Gouichi Niiyama, Akiyoshi Izumi, Ayumi Kamei, Hideji Ikeda, Mitsuhiko Suehiro, Kazumi Togawa, Takayo Sasagawa, Misako Okita, Hajime Nakamura, Junji Yodoi, Gotaro YamadaControl of oxidative stress and reduction in biochemical markers by Vitamin E treatment in patients with nonalcoholic steatohepatitis: a pilot studyHepatology Research.()
    7. Liver Enzymes - Chee NM, Sinnanaidu RP, Chan WKVitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.J Gastroenterol Hepatol.(2024 Aug 16)
    8. Liver Enzymes - Abdelmalek MF, Angulo P, Jorgensen RA, Sylvestre PB, Lindor KDBetaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot studyAm J Gastroenterol.(2001 Sep)
    9. Liver Enzymes - Sandeep Mukherjee, Tamara Bernard, Kusum Kharbanda, Anthony J. Barak, Michael F. Sorrell, Dean J. TumaImpact of Betaine on Hepatic Fibrosis and Homocysteine in Nonalcoholic Steatohepatitis - A Prospective, Cohort StudyThe Open Translational Medicine Journal.()
    10. Liver Enzymes - Zhong S, Fan Y, Yan Q, Fan X, Wu B, Han Y, Zhang Y, Chen Y, Zhang H, Niu JThe therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: A meta-analysis (PRISMA) of randomized control trialsMedicine (Baltimore).(2017 Dec)
    11. Liver Enzymes - de Avelar CR, Pereira EM, de Farias Costa PR, de Jesus RP, de Oliveira LPMEffect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis.World J Gastroenterol.(2017-Jul-21)
    12. Liver Enzymes - Malaguarnera M, Gargante MP, Russo C, Antic T, Vacante M, Malaguarnera M, Avitabile T, Li Volti G, Galvano FL-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trialAm J Gastroenterol.(2010 Jun)
    13. Weight - Amiri-Moghadam S, et alEffects of L-carnitine supplementation on body composition in patients with nonalcoholic steatohepatitis (NASH)CURR TOP NUTRACEUT R.()
    14. Oxidative Stress Biomarkers - Amiri-Moghadam s, et alEffects of L-carnitine supplementation on inflammatory factors and malondialdehyde in patients with nonalcoholic steatohepatitis (NASH)CURR TOP NUTRACEUT R.()
    15. Liver Enzymes - Jingwen Zhou, Yidi Chen, Jun Yu, Tianci Li, Ziyu Lu, Yan Chen, Xiaolong Zhang, Fang YeThe efficacy of novel metabolic targeted agents and natural plant drugs for nonalcoholic fatty liver disease treatment: A PRISMA-compliant network meta-analysis of randomized controlled trialsMedicine (Baltimore).(2021 Mar 26)
    16. Liver Enzymes - Musazadeh V, Assadian K, Rajabi F, Faghfouri AH, Soleymani Y, Kavyani Z, Najafiyan BThe effect of synbiotics on liver enzymes, obesity indices, blood pressure, lipid profile, and inflammation in patients with non-alcoholic fatty liver: A systematic review and meta-analysis of randomized controlled trials.Pharmacol Res.(2024 Sep 4)