What are some of the main medical treatments for pneumonia?

    Last Updated: October 25, 2023

    Antibiotics are the first-line treatment for most cases of pneumonia. The choice of antibiotic, however, will depend upon the clinician weighing the risks and benefits of antibiotic therapy, the person’s medical history, and local epidemiological data (community outbreaks, microbe prevalence, etc.).[1] If testing (e.g., blood and sputum cultures, nasal swabs) indicates the causative pathogen is not a bacteria, an antiviral (to fight viruses) or an antifungal (to fight fungi) may be given.

    Corticosteroids are not indicated for use in people with uncomplicated pneumonia; instead, they are reserved for people whose pneumonia is exacerbating preexisting reactive airway disease (e.g., COPD), or who are critically ill (e.g., septic shock) and not responding to usual treatments. Moderate to severe cases of pneumonia may also require supportive treatments, such as oxygen therapy, IV fluids, blood pressure medications, and airway/breathing support. [2] Aerosolized antibiotics are sometimes used in hospital settings for ventilator-associated pneumonia, but there is no robust evidence to support their efficacy. [3]

    References

    1. ^Torres A, Cilloniz C, Niederman MS, Menéndez R, Chalmers JD, Wunderink RG, van der Poll TPneumonia.Nat Rev Dis Primers.(2021-Apr-08)
    2. ^Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, Cooley LA, Dean NC, Fine MJ, Flanders SA, Griffin MR, Metersky ML, Musher DM, Restrepo MI, Whitney CGDiagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America.Am J Respir Crit Care Med.(2019-Oct-01)
    3. ^Xu F, He LL, Che LQ, Li W, Ying SM, Chen ZH, Shen HHAerosolized antibiotics for ventilator-associated pneumonia: a pairwise and Bayesian network meta-analysis.Crit Care.(2018-Nov-15)