Preeclampsia is diagnosed by the onset of high blood pressure and signs of organ damage after 20 weeks gestation (though very rarely it may occur earlier). The formal criteria for a diagnosis include:
- Blood pressure elevation as follows:
- Systolic blood pressure elevation of ≥140 mmHg or diastolic blood pressure elevation of ≥90 mmHg on two occasions at least four hours apart, OR
- blood pressure elevation of ≥ 160/110 mmHg on two occasions at least several minutes apart
- Proteinuria (≥ 300 mg/24 hours, or protein/creatinine ratio of ≥ 0.3, or +2 by dipstick testing if quantitative measurement is not available)[1][2][3][4], OR at least one of the following signs:
- Elevated creatinine (>1 mg/dL)[5]
- Low platelets (<100 x 109/L)[6]
- Liver dysfunction (elevated transaminases)
- Fluid in the lungs (pulmonary edema)
- Neurological dysfunction (hyperreflexia, visual disturbances, headache)[5][7]
References
- ^Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy.Am J Obstet Gynecol.(2000 Jul)
- ^Wu P, Haththotuwa R, Kwok CS, Babu A, Kotronias RA, Rushton C, Zaman A, Fryer AA, Kadam U, Chew-Graham CA, Mamas MAPreeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.Circ Cardiovasc Qual Outcomes.(2017-Feb)
- ^Khaing W, Vallibhakara SA, Tantrakul V, Vallibhakara O, Rattanasiri S, McEvoy M, Attia J, Thakkinstian ACalcium and Vitamin D Supplementation for Prevention of Preeclampsia: A Systematic Review and Network Meta-Analysis.Nutrients.(2017-Oct-18)
- ^Hofmeyr GJ, Lawrie TA, Atallah AN, Duley L, Torloni MRCalcium supplementation during pregnancy for preventing hypertensive disorders and related problemsCochrane Database Syst Rev.(2014 Jun 24)
- ^Ahmed R, Dunford J, Mehran R, Robson S, Kunadian VPre-eclampsia and future cardiovascular risk among women: a review.J Am Coll Cardiol.(2014-May-13)
- ^Ciobanu AM, Colibaba S, Cimpoca B, Peltecu G, Panaitescu AMThrombocytopenia in Pregnancy.Maedica (Bucur).(2016-Mar)
- ^American College of Obstetricians and GynecologistsGestational Hypertension and PreeclampsiaObstetrics & Gynecology.(June 2020)