Have any supplements been studied for SIBO?

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    Last Updated: October 13, 2024

    Probiotics may be useful for treating SIBO, but it’s not clear which strains (or combinations of strains) are optimal.[1][2] Some research has also shown good results from probiotics used alongside during or immediately after antibiotic treatment.[3][1]

    Other treatments, such as prebiotics, curcumin, ursodeoxycholic acid, daikenchuto (a traditional Japanese herbal preparation), Serum-derived bovine immunoglobulin/protein isolate, and some antimicrobial herbs have also been studied, but there isn’t enough evidence to recommend their use.

    References

    1. ^Changqing Zhong, Changmin Qu, Baoyan Wang, Shuwen Liang, Bolun ZengProbiotics for Preventing and Treating Small Intestinal Bacterial Overgrowth: A Meta-Analysis and Systematic Review of Current EvidenceJ Clin Gastroenterol.(2017 Apr)
    2. ^Konstantinos Leventogiannis, Paraskevas Gkolfakis, Georgios Spithakis, Aikaterini Tsatali, Aikaterini Pistiki, Athanasios Sioulas, Evangelos J Giamarellos-Bourboulis, Konstantinos TriantafyllouEffect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial OvergrowthProbiotics Antimicrob Proteins.(2019 Jun)
    3. ^Grettel García-Collinot, Eduardo Osiris Madrigal-Santillán, Michel A Martínez-Bencomo, Rosa A Carranza-Muleiro, Luis J Jara, Olga Vera-Lastra, Daniel H Montes-Cortes, Gabriela Medina, María Pilar Cruz-DomínguezEffectiveness of Saccharomyces boulardii and Metronidazole for Small Intestinal Bacterial Overgrowth in Systemic SclerosisDig Dis Sci.(2020 Apr)