When it comes to metabolic health, particularly liver enzymes, further evidence exists that artichoke leaf extract (50–3,000 mg per day) taken over periods of 4–32 weeks could reduce ALT and AST.[1][2][3][4][5] Several of these studies were also done in participants who were diagnosed with nonalcoholic fatty liver disease and would suggest that greater effects may occur with higher amounts taken over smaller time periods.[1][2][5]
A few studies suggest that artichoke leaf extract (100–3,000 mg per day over 6–12 weeks) could produce small improvements in waist circumference, blood glucose, and symptoms of dyspepsia.[6][7][3]