Have any supplements been studied for mild cognitive impairment?

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    Last Updated: May 16, 2025

    Several supplements — including omega-3 fatty acids, probiotics, and various vitamins, have been studied for mild cognitive impairment — but current evidence does not support their effectiveness in improving cognitive function or preventing dementia. More high-quality, large-scale, randomized controlled trials are needed to draw definitive conclusions.

    The effects of several supplements have been studied in people with mild cognitive impairment. These include omega-3 fatty acids, probiotics, ginkgo biloba, B vitamins, vitamin C, vitamin D, vitamin E, etc. However, the current evidence does not support the use of any supplement in people with mild cognitive impairment for improving cognitive function or preventing dementia.[1][2][3][4] That said, the current evidence is limited, and more high-quality large-scale randomized controlled trials are needed to make definitive conclusions.