Have any supplements been studied for SIBO?

    Written by:

    Fact-checked

    by:

    Last Updated: May 16, 2025

    Probiotics may be beneficial for treating small intestinal bacterial overgrowth (SIBO), although the optimal strains are unclear, and they have shown positive results when used with antibiotics. Other treatments (like prebiotics, curcumin, and certain herbal preparations) have been studied, but there is insufficient evidence to recommend them.

    Probiotics may be useful for treating SIBO, but it’s not clear which strains (or combinations of strains) are optimal.[1][2] Some research has also shown good results from probiotics used alongside during or immediately after antibiotic treatment.[3][1]

    Other treatments, such as prebiotics, curcumin, ursodeoxycholic acid, daikenchuto (a traditional Japanese herbal preparation), Serum-derived bovine immunoglobulin/protein isolate, and some antimicrobial herbs have also been studied, but there isn’t enough evidence to recommend their use.

    Have any supplements been studied for SIBO? - Examine