Chronic stress is implicated in the development and progression of CAD over time, and acute bouts of stress can trigger rapid progression of CAD or the underlying atherosclerosis.[1] When your fight-or-flight response is dialed up constantly, it can increase white blood cells called leukocytes, which play a direct role in advancing atherosclerosis and increase inflammation throughout the body and the inflammation of the clogged arteries.[2] Acute and chronic stress raises blood pressure — which encourages atherosclerosis — and acute stress can precipitate a blockage of the heart (A.K.A. thrombosis) leading to decreased blood flow, reduced oxygenation, and damage to the heart itself. [3] Meditation and interventions to lower stress may reduce the risk of getting CAD in the first place, as well as reducing downstream effects of CAD like stroke and heart attacks.[4][5]