In healthy adults, caffeine intake of up to 400 mg per day has not been linked to increases in cardiovascular disease risk.[1][2] However, the evidence is uncertain regarding the long-term effects of regular caffeine intake for people with high blood pressure or pre-existing heart conditions.[1][3] This also applies to people for whom stimulants in general are not recommended. Low to moderate intake may be generally safe, but this must be assessed on a case-by-case basis in consultation with a physician.