There are no Food and Drug Administration-approved medications for treating NAFLD. Current guidelines suggest that pharmacological treatment should be reserved for people with biopsy-proven NASH.[1] Off-label medications are mainly used for treating risk factors (i.e., obesity, insulin resistance, hypertension, dyslipidemia) with the aim of preventing disease progression.
What are some of the main medical treatments for NAFLD?
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•Last Updated: May 16, 2025
There are no FDA-approved medications specifically for treating nonalcoholic fatty liver disease (NAFLD), and pharmacological treatment is recommended only for people with biopsy-proven nonalcoholic steatohepatitis (NASH). Off-label medications are primarily used to address risk factors such as obesity and insulin resistance to help prevent disease progression.