NAFLD reflects an imbalance of energy metabolism in the liver: more energy enters the liver than it can dispose of, resulting in a net accumulation of energy as triglycerides.[1] Overnutrition and sedentary behavior primarily lead to the development of NAFLD, but there are a variety of other factors that further influence the development and progression of the disease, including genetics, aging, fat tissue dysfunction, gut dysbiosis, and insulin resistance.[2][3]
Causes of NAFLD
Adapted from Stefan, Häring & Cusi, 2019[3]