What risks are associated with micronutrient deficiencies during pregnancy?

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    Last Updated: May 16, 2025

    Micronutrient deficiencies during pregnancy can lead to serious risks for both the parent and child, including iron deficiency anemia, neural tube defects from low folate, and irreversible neurological damage from severe iodine deficiency. Additionally, deficiencies in calcium, vitamin D, and selenium are associated with complications such as hypertension, preeclampsia, and poor pregnancy outcomes.

    Micronutrient deficiencies during pregnancy can have significant consequences on both the mother and the baby. Here are some of the most common deficiencies and their associated risks:

    Iron deficiency during pregnancy is among the most common nutrient deficiencies. Low iron levels can lead to iron deficiency anemia (IDA) which can have negative consequences both on the mother and the baby.[1]

    Low folate levels are associated with infant neural tube defects.[1]

    Severe iodine deficiency can cause irreversible neurological damage to the fetus, resulting in congenital hypothyroidism, which, if not treated within a month of birth, can result in permanent intellectual disability.[2][3] Iodine deficiency is rare in most countries, as in the majority of countries most people get enough iodine from food; however, sub-Saharan Africa and South Asia still have relatively high incidences of iodine deficiency.[4]

    Calcium and vitamin D deficiencies during pregnancy are associated with hypertension (high blood pressure) and increased risk of preeclampsia (a pregnancy complication characterized by high blood pressure), as well as high levels of protein in the urine, all of which can have negative consequences for both the mother and the fetus.[5][1][6]

    Selenium deficiency has been associated with poor pregnancy outcomes, including increased incidences of recurrent miscarriage, preeclampsia, intrauterine growth restriction, and preterm birth.[7]