Examine Database: Mucositis Symptoms
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Honey | B | ||
| Probiotics | A | ||
| Zinc | C | ||
| Low-Level Laser Therapy | |||
| Hyaluronic Acid | |||
| Curcumin | |||
| Kefir | |||
| Yarrow | |||
| Calendula Officinalis |
Research FeedRead all studies
Does curcumin improve mucositis symptoms?
In this meta-analysis of 6 randomized controlled trials in participants undergoing therapy for cancer, interventions involving curcumin improved mucositis symptoms and oral pain.
Does adding mulberry juice to mouthwash improve its effect on mucositis?
Does a honey-and-ginger mouthwash improve mucositis with chemotherapy?
The role of nutritional support in mucositis risk in people undergoing chemotherapy for head and neck cancer
Honey for chemotherapy-induced mucositis
Examine Database References
- Zinc - Ertekin MV, Koç M, Karslioglu I, Sezen OZinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized studyInt J Radiat Oncol Biol Phys.(2004 Jan 1)
- Zinc - Mansouri A, Hadjibabaie M, Iravani M, Shamshiri AR, Hayatshahi A, Javadi MR, Khoee SH, Alimoghaddam K, Ghavamzadeh AThe effect of zinc sulfate in the prevention of high-dose chemotherapy-induced mucositis: a double-blind, randomized, placebo-controlled studyHematol Oncol.(2012 Mar)
- Curcumin - Chainani-Wu N, Madden E, Lozada-Nur F, Silverman S JrHigh-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planusJ Am Acad Dermatol.(2012 May)
- Zinc - Sangthawan D, Phungrassami T, Sinkitjarurnchai WA randomized double-blind, placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patientsJ Med Assoc Thai.(2013 Jan)
- Zinc - Arbabi-kalati F, Arbabi-kalati F, Deghatipour M, Ansari Moghadam AEvaluation of the efficacy of zinc sulfate in the prevention of chemotherapy-induced mucositis: a double-blind randomized clinical trialArch Iran Med.(2012 Jul)
- Kefir - E Topuz, D Derin, G Can, E Kürklü, S Cinar, F Aykan, A Cevikbaş, R Dişçi, Z Durna, B Sakar, S Saglam, H Tanyeri, G Deniz, U Gürer, F Taş, N Guney, A AydinerEffect of oral administration of kefir on serum proinflammatory cytokines on 5-FU induced oral mucositis in patients with colorectal cancerInvest New Drugs.(2008 Dec)
- Kefir - Gulbeyaz Can, Erkan Topuz, Duygu Derin, Zehra Durna, Adnan AydinerEffect of kefir on the quality of life of patients being treated for colorectal cancerOncol Nurs Forum.(2009 Nov)
- Calendula Officinalis - Babaee N, Moslemi D, Khalilpour M, Vejdani F, Moghadamnia Y, Bijani A, Baradaran M, Kazemi MT, Khalilpour A, Pouramir M, Moghadamnia AAAntioxidant capacity of calendula officinalis flowers extract and prevention of radiation induced oropharyngeal mucositis in patients with head and neck cancers: a randomized controlled clinical study.Daru.(2013-Mar-07)
- Yarrow - Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MA New mouthwash for Chemotherapy Induced Stomatitis.Nurs Midwifery Stud.(2014-Sep)
- Hyaluronic Acid - Tai RZ, Loh EW, Tsai JT, Tam KWEffect of hyaluronic acid on radiotherapy-induced mucocutaneous side effects: a meta-analysis of randomized controlled trials.Support Care Cancer.(2022-Jun)
- Yarrow - Miranzadeh S, Adib-Hajbaghery M, Soleymanpoor L, Ehsani MEffect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial.Eur J Oncol Nurs.(2015-Jun)
- Low-Level Laser Therapy - Jin X, Fan Y, Guo C, Yang J, Zeng YC, Zhang JEEffect of nonpharmacological interventions on nutrition status, complications and quality of life in head and neck cancer patients undergoing radiotherapy: A systematic review and meta-analysis.Int J Nurs Pract.(2024 Jun 5)
- Probiotics - Lin P, Zhuang J, Lai J, Cui J, Jiang D, Huang JEfficacy of probiotics in the treatment of oral mucositis in head and neck cancer patients: A systematic review and meta-analysis.Microb Pathog.(2024 Jul 4)
- Probiotics - Zhu Z, Pan W, Ming X, Wu J, Zhang X, Miao J, Cui WThe effect of probiotics on severe oral mucositis in cancer patients undergoing chemotherapy and/or radiotherapy: A meta-analysis.J Stomatol Oral Maxillofac Surg.(2024 Aug 24)
- Honey - Lee CC, Chen YW, Kang YN, Chen JH, Chen C, Lu CY, Huang TW, Gautama MSNEfficacy of natural products in preventing oral mucositis resulting from cancer therapies: A network meta-analysis of randomized controlled trials.Crit Rev Oncol Hematol.(2024 Jul)
- Honey - Xu JL, Xia R, Sun ZH, Sun L, Min X, Liu C, Zhang H, Zhu YMEffects of honey use on the management of radio/chemotherapy-induced mucositis: a meta-analysis of randomized controlled trials.Int J Oral Maxillofac Surg.(2016 Dec)
- Honey - Co JL, Mejia MB, Que JC, Dizon JMEffectiveness of honey on radiation-induced oral mucositis, time to mucositis, weight loss, and treatment interruptions among patients with head and neck malignancies: A meta-analysis and systematic review of literature.Head Neck.(2016 Jul)
- Honey - Liu TM, Luo YW, Tam KW, Lin CC, Huang TWProphylactic and therapeutic effects of honey on radiochemotherapy-induced mucositis: a meta-analysis of randomized controlled trials.Support Care Cancer.(2019 Jul)
- Honey - Tian X, Xu L, Liu X, Wang CC, Xie W, Jiménez-Herrera MF, Chen WImpact of honey on radiotherapy-induced oral mucositis in patients with head and neck cancer: a systematic review and meta-analysis.Ann Palliat Med.(2020 Jul)
- Honey - An W , Li S , Qin L Role of honey in preventing radiation-induced oral mucositis: a meta-analysis of randomized controlled trials.Food Funct.(2021 Apr 21)
- Honey - Lima ICGDS, de Fátima Souto Maior L, Gueiros LAM, Leão JC, Higino JS, Carvalho AATClinical applicability of natural products for prevention and treatment of oral mucositis: a systematic review and meta-analysis.Clin Oral Investig.(2021 Jun)
- Honey - Raza A, Karimyan N, Watters A, Emperumal CP, Al-Eryani K, Enciso REfficacy of oral and topical antioxidants in the prevention and management of oral mucositis in head and neck cancer patients: a systematic review and meta-analyses.Support Care Cancer.(2022 Nov)
- Honey - Yang C, Gong G, Jin E, Han X, Zhuo Y, Yang S, Song B, Zhang Y, Piao CTopical application of honey in the management of chemo/radiotherapy-induced oral mucositis: A systematic review and network meta-analysis.Int J Nurs Stud.(2019 Jan)
- Honey - Yu YT, Deng JL, Jin XR, Zhang ZZ, Zhang XH, Zhou XEffects of 9 oral care solutions on the prevention of oral mucositis: a network meta-analysis of randomized controlled trials.Medicine (Baltimore).(2020 Apr)
- Curcumin - Amatto PPG, Chaves L, França SC, Carvalho JCT, Carmona F, Pereira AMSEfficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and meta-analysis.Front Pharmacol.(2025)