Plasma Endorphins

    Last Updated: August 16, 2022

    Endorphins are naturally produced peptides (i.e., small amino acid chains) that have opioid activity. They are made and stored in the pituitary gland, and play a major role in the body's pain response. Their release can also be triggered by exercise, meditation, and laughter.

    examine-databaseExamine Database
    49 participants in 3 trials

    Examine Database: Plasma Endorphins

    Gamma Oryzanol
    D
    No effect
    Sodium Bicarbonate
    C
    Moderate Decrease
    DHEA
    C
    Small Increase

    Examine Database References

    1. DHEA - Alessandro D Genazzani, Massimo Stomati, Francesca Bernardi, Matteo Pieri, Lucio Rovati, Andrea R GenazzaniLong-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroidsFertil Steril.(2003 Dec)
    2. Gamma Oryzanol - Fry AC, Bonner E, Lewis DL, Johnson RL, Stone MH, Kraemer WJThe effects of gamma-oryzanol supplementation during resistance exercise trainingInt J Sport Nutr.(1997 Dec)
    3. Sodium Bicarbonate - Taylor DV, Boyajian JG, James N, Woods D, Chicz-Demet A, Wilson AF, Sandman CAAcidosis stimulates beta-endorphin release during exerciseJ Appl Physiol.(1994 Oct)