Alpha-Ketoglutarate

    Written by:
    Megan Michaux
    Fact-checked by:
    Nick Milazzo
    Last Updated: January 16, 2023

    Alpha-ketoglutarate (AKG) is an important biological compound that plays a central role in regulating energy production through the Krebs cycle, which is the main way cells create energy. AKG has been used to increase muscle protein synthesis, but may also be useful as a supplement for longevity and healthy aging.

    Overview

    Dosage Information

    In research, the dosages used range from 3.6 g to 6 g, with higher dosing in people who have suffered burns, but a recommended daily dose has not yet been established.[1] Since the effects are dose-dependent, finding an accurate dosing recommendation will be an important part of ongoing research.[2]

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