Inulin

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    Last Updated: November 2, 2023

    Inulin is a type of soluble fiber that can be taken as a supplement or found naturally in foods (e.g., Jerusalem artichokes, chicory, asparagus, garlic, onions, wheat, bananas). Inulin can have prebiotic effects on the gut microbiome, leading to increases in the abundance of potentially beneficial bacteria, such as Bifidobacterium spp.. Inulin may have various benefits on gut and overall health, but clinical trials tend to report inconsistent results, which may be due to variability in baseline microbiomes, habitual diets, and health status.

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    Examine Database: Inulin

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    Examine Database References

    1. Blood glucose - Wang L, Yang H, Huang H, Zhang C, Zuo HX, Xu P, Niu YM, Wu SSInulin-type fructans supplementation improves glycemic control for the prediabetes and type 2 diabetes populations: results from a GRADE-assessed systematic review and dose-response meta-analysis of 33 randomized controlled trials.J Transl Med.(2019-Dec-05)
    2. Blood glucose - Rao M, Gao C, Xu L, Jiang L, Zhu J, Chen G, Law BYK, Xu YEffect of Inulin-Type Carbohydrates on Insulin Resistance in Patients with Type 2 Diabetes and Obesity: A Systematic Review and Meta-Analysis.J Diabetes Res.(2019)
    3. Low-density lipoprotein (LDL) - Liu F, Prabhakar M, Ju J, Long H, Zhou HWEffect of inulin-type fructans on blood lipid profile and glucose level: a systematic review and meta-analysis of randomized controlled trials.Eur J Clin Nutr.(2017-Jan)
    4. C-Reactive Protein (CRP) - Dayanne da Silva Borges, Ricardo Fernandes, Arthur Thives Mello, Ethiene da Silva Fontoura, Adair Roberto Soares Dos Santos, Erasmo Benicio Santos de Moraes TrindadePrebiotics may reduce serum concentrations of C-reactive protein and ghrelin in overweight and obese adults: a systematic review and meta-analysisNutr Rev.(2020 Mar 1)
    5. Constipation Signs and Symptoms - Collado Yurrita L, San Mauro Martín I, Ciudad-Cabañas MJ, Calle-Purón ME, Hernández Cabria MEffectiveness of inulin intake on indicators of chronic constipation; a meta-analysis of controlled randomized clinical trials.Nutr Hosp.(2014-Aug-01)
    6. Bifidobacterium Abundance - Dou Y, Yu X, Luo Y, Chen B, Ma D, Zhu JEffect of Fructooligosaccharides Supplementation on the Gut Microbiota in Human: A Systematic Review and Meta-Analysis.Nutrients.(2022-Aug-12)
    7. Migraine Frequency - Vajdi M, Khorvash F, Askari GA randomized, double-blind, placebo-controlled parallel trial to test the effect of inulin supplementation on migraine headache characteristics, quality of life and mental health symptoms in women with migraine.Food Funct.(2024 Sep 30)
    8. Liver Fat - Mayengbam S, Raman M, Parnell JA, Eksteen B, Lambert JE, Eller LK, Nicolucci AC, Aktary ML, Reimer RAEffects of combined prebiotic fiber supplementation and weight loss counseling in adults with metabolic dysfunction-associated steatotic liver disease: a randomized controlled trial.Eur J Nutr.(2025 Apr 2)