Overview
What is kanna?
What are kanna’s main benefits?
How does kanna work?
What are kanna’s main drawbacks?
Dosage information
Currently studies using kanna have used the brand name Zembrin at doses of 8 to25 mg prior to cognitive testing. This brand name is a 2:1 concentration of kanna based on dry weight and is considered equivalent to 16 to 50 mg of the dry weight of the plant itself.
Kanna has been studied as oral administration (capsules) but traditionally the leaves have been chewed and saliva swallowed for similar effects.
Optimal frequency of dosing (i.e., either only on testing days or daily) is currently not known.
Examine Database: Kanna
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Frequently asked questions
Can kanna be used for pain?
Can kanna protect against neurocognitive disorders?
What are other names for Kanna?
Update History
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Research Breakdown
References
Examine Database References
- Heart Rate - Nell H, Siebert M, Chellan P, Gericke NA randomized, double-blind, parallel-group, placebo-controlled trial of Extract Sceletium tortuosum (Zembrin) in healthy adultsJ Altern Complement Med.(2013 Nov)
- Sleep Quality - Chiu S, Gericke N, Farina-Woodbury M, Badmaev V, Raheb H, Terpstra K, Antongiorgi J, Bureau Y, Cernovsky Z, Hou J, Sanchez V, Williams M, Copen J, Husni M, Goble LProof-of-Concept Randomized Controlled Study of Cognition Effects of the Proprietary Extract Sceletium tortuosum (Zembrin) Targeting Phosphodiesterase-4 in Cognitively Healthy Subjects: Implications for Alzheimer's DementiaEvid Based Complement Alternat Med.(2014)
- Stress Signs and Symptoms - Terburg D, Syal S, Rosenberger LA, Heany S, Phillips N, Gericke N, Stein DJ, van Honk JAcute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamusNeuropsychopharmacology.(2013 Dec)