Lion's Mane

    Written by:
    Giulia Guerrini

    Fact-checked

    by:

    Nick Milazzo
    Last Updated: October 30, 2023

    Lion's mane, Hericium erinaceus, is a culinary and medicinal mushroom. Lion’s mane appears to have neuroprotective and antioxidant properties in the brain.

    18 references on this page
    101 participants in 3 trials

    Overview

    Dosage information

    Clinical studies investigating lion's mane mushroom have utilized dosages ranging from 1050–3000 mg, divided into three to four daily doses. Nevertheless, the optimal dose remains uncertain, and the minimum effective concentration may vary depending on the specific target system.[1][2][3][4]

    Examine Database: Lion's Mane

    Research FeedRead all studies

    Frequently asked questions

    Update History

    Research Breakdown

    Examine Database References

    1. Depression Symptoms - Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki KReduction of depression and anxiety by 4 weeks Hericium erinaceus intakeBiomed Res.(2010 Aug)
    2. Alzheimer's Disease Symptoms - I-Chen Li, Han-Hsin Chang, Chuan-Han Lin, Wan-Ping Chen, Tsung-Han Lu, Li-Ya Lee, Yu-Wen Chen, Yen-Po Chen, Chin-Chu Chen, David Pei-Cheng LinPrevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled StudyFront Aging Neurosci.(2020 Jun 3)
    3. Cognitive Decline - Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida TImproving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trialPhytother Res.(2009 Mar)