Overview

What is lion’s mane?

What are the main benefits of lion’s mane?

What are the main drawbacks of lion's mane?

How does lion’s mane work?

Dosage information

Clinical studies investigating lion's mane mushroom have utilized dosages ranging from 1050–3000 mg, divided into three to four daily doses. Nevertheless, the optimal dose remains uncertain, and the minimum effective concentration may vary depending on the specific target system.^[1]^[2]^[3]^[4]

Examine Database: Lion's Mane

The conditions below have no primary outcomes

Health Condition/Goal	Health Outcome	Grade	Evidence
Alzheimer’s Disease	1 primary outcome	D	1 Study
Anxiety	1 primary outcome		1 Study
Mild Cognitive Impairment	0 outcomes	-	1 Study

Alzheimer’s Disease

1 primary outcome

1 Study

Anxiety

1 primary outcome

1 Study

Mild Cognitive Impairment

0 outcomes

1 Study

Alzheimer’s Disease

Anxiety

The conditions below have no primary outcomes

Mild Cognitive Impairment

Research FeedRead all studies

Does lion’s mane improve cognition or mood after a single dose?

In this randomized crossover study in 18 young men and women without known health conditions, one-time supplementation with lion’s mane had no effect on cognition or mood.

Can cognitive decline be reversed?

Lion’s mane mushroom may not improve cognitive function among young adults

Frequently asked questions

Where do the many names of lion's mane come from?

What is the nutritional value of lion’s mane?

Does lion’s mane benefit metabolic health?

What are some other potential benefits of lion’s mane?

In what other context is lion’s mane used?

Update History

Small correction
minor

Research written by

Giulia Guerrini

Edited by

Natalka Roshak

Reviewed by

Nick Milazzo

Standard FAQ update
major

Research written by

Giulia Guerrini

Edited by

Natalka Roshak

Reviewed by

Nick Milazzo

Research Breakdown

References

Examine Database References

Depression Symptoms - Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki KReduction of depression and anxiety by 4 weeks Hericium erinaceus intakeBiomed Res.(2010 Aug)
Alzheimer's Disease Symptoms - I-Chen Li, Han-Hsin Chang, Chuan-Han Lin, Wan-Ping Chen, Tsung-Han Lu, Li-Ya Lee, Yu-Wen Chen, Yen-Po Chen, Chin-Chu Chen, David Pei-Cheng LinPrevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled StudyFront Aging Neurosci.(2020 Jun 3)
Cognitive Decline - Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida TImproving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trialPhytother Res.(2009 Mar)

Lion's Mane

Overview

What is lion’s mane?

What are the main benefits of lion’s mane?

What are the main drawbacks of lion's mane?

How does lion’s mane work?

Dosage informationMedical disclaimer

Examine Database: Lion's Mane

Research FeedRead all studies

Frequently asked questions

Where do the many names of lion's mane come from?

What is the nutritional value of lion’s mane?

Does lion’s mane benefit metabolic health?

What are some other potential benefits of lion’s mane?

In what other context is lion’s mane used?

Update History

Small correctionminor

Standard FAQ updatemajor

Research Breakdown

References

Examine Database References

Research FeedRead all studies

Examine Database References

Examine Database: Lion's Mane

Dosage information

Small correction
minor

Standard FAQ update
major