References
- ^Palmer RD, Elnashar MM, Vaccarezza MPrecursor comparisons for the upregulation of nicotinamide adenine dinucleotide. Novel approaches for better aging.Aging Med (Milton).(2021-Sep)
NMN is a naturally occurring form of Vitamin B3 that is studied for slowing aging and for preventing diseases of aging. Dietary NMN is converted to nicotinamide adenine dinucleotide (NAD+), a coenzyme in all living cells which is required for numerous biological processes. NAD+ levels naturally decline with age, reaching less than 50% of youthful levels by middle age.[1] Decreased NAD+ levels have been attributed to increased inflammation and oxidative stress as well as to the development of age-related conditions such as hypertension, cognitive decline, and type 2 diabetes. While the anti-aging effects of NMN in rodents are well-established, studies are ongoing to determine whether equally impressive anti-aging effects are possible in humans.