Anxiety

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    Nick Milazzo, Natalka Roshak

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    Mike Murray, Katie Jantz
    Last Updated: January 6, 2025

    Anxiety disorders are a group of disorders characterized by symptoms of excessive anxiety and/or fear. Anxiety itself, unlike fear, is persistent and future oriented. There are many types of anxiety disorders, including generalized anxiety disorder, social anxiety disorder, phobias, and panic disorder.

    22 references on this page
    9,134 participants in 17 trials and 12 meta-analyses

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    Examine Database: Anxiety

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    Examine Database References

    1. Anxiety Symptoms - Andrade C, Aswath A, Chaturvedi SK, Srinivasa M, Raguram RA double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somniferaIndian J Psychiatry.(2000 Jul)
    2. Anxiety Symptoms - Cooley K, Szczurko O, Perri D, Mills EJ, Bernhardt B, Zhou Q, Seely DNaturopathic care for anxiety: a randomized controlled trial ISRCTN78958974PLoS One.(2009 Aug 31)
    3. Anxiety Symptoms - Camellia Akhgarjand, Farzaneh Asoudeh, Amir Bagheri, Zahra Kalantar, Zahra Vahabi, Sakineh Shab-Bidar, Hamid Rezvani, Kurosh DjafarianDoes Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trialsPhytother Res.(2022 Aug 25)
    4. Anxiety Symptoms - Alireza Milajerdi, Shima Jazayeri, Elham Shirzadi, Najmeh Hashemzadeh, Atieh Azizgol, Abolghassem Djazayery, Ahmad Esmaillzadeh, Shahin AkhondzadehThe effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus: A double-blind, randomized and placebo-controlled clinical trialComplement Ther Med.(2018 Dec)
    5. Anxiety Symptoms - Ehsan Moazen-Zadeh, Seyed Hesameddin Abbasi, Hamideh Safi-Aghdam, Nazila Shahmansouri, Akram Arjmandi-Beglar, Azita Hajhosseinn Talasaz, Abbas Salehiomran, Saeedeh Forghani, Shahin AkhondzadehEffects of Saffron on Cognition, Anxiety, and Depression in Patients Undergoing Coronary Artery Bypass Grafting: A Randomized Double-Blind Placebo-Controlled TrialJ Altern Complement Med.(2018 Apr)
    6. Anxiety Symptoms - A Ghajar, S M Neishabouri, N Velayati, L Jahangard, N Matinnia, M Haghighi, A Ghaleiha, M Afarideh, S Salimi, A Meysamie, S AkhondzadehCrocus sativus L. versus Citalopram in the Treatment of Major Depressive Disorder with Anxious Distress: A Double-Blind, Controlled Clinical TrialPharmacopsychiatry.(2017 Jul)
    7. Anxiety Symptoms - Mohsen Mazidi, Maryam Shemshian, Seyed Hadi Mousavi, Abdolreza Norouzy, Tayebe Kermani, Toktam Moghiman, Akram Sadeghi, Naghme Mokhber, Majid Ghayour-Mobarhan, Gordon A A FernsA double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depressionJ Complement Integr Med.(2016 Jun 1)
    8. Anxiety Symptoms - Simon B Goldberg, Brian T Pace, Christopher R Nicholas, Charles L Raison, Paul R HutsonThe experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysisPsychiatry Res.(2020 Feb)
    9. Suicidal Thoughts - Zeifman RJ, Yu D, Singhal N, Wang G, Nayak SM, Weissman CRDecreases in Suicidality Following Psychedelic Therapy: A Meta-Analysis of Individual Patient Data Across Clinical Trials.J Clin Psychiatry.(2022-Jan-18)
    10. Anxiety Symptoms - Amsterdam JD, Yao Y, Mao JJ, Soeller I, Rockwell K, Shults JRandomized, double-blind, placebo-controlled trial of Cimicifuga racemosa (black cohosh) in women with anxiety disorder due to menopauseJ Clin Psychopharmacol.(2009 Oct)
    11. Anxiety Symptoms - Sarris J, Byrne GJ, Cribb L, Oliver G, Murphy J, Macdonald P, Nazareth S, Karamacoska D, Galea S, Short A, Ee C, Birling Y, Menon R, Ng CHL-theanine in the adjunctive treatment of generalized anxiety disorder: A double-blind, randomised, placebo-controlled trialJ Psychiatr Res.(2019 Mar)
    12. Anxiety Symptoms - Geier FP, Konstantinowicz TKava treatment in patients with anxietyPhytother Res.(2004 Apr)
    13. Anxiety Symptoms - Volz HP, Kieser MKava-kava extract WS 1490 versus placebo in anxiety disorders--a randomized placebo-controlled 25-week outpatient trialPharmacopsychiatry.(1997 Jan)
    14. Anxiety Symptoms - Lehrl SClinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trialJ Affect Disord.(2004 Feb)
    15. Anxiety Symptoms - Malsch U, Kieser MEfficacy of kava-kava in the treatment of non-psychotic anxiety, following pretreatment with benzodiazepinesPsychopharmacology (Berl).(2001 Sep)
    16. Anxiety Symptoms - Gastpar M, Klimm HDTreatment of anxiety, tension and restlessness states with Kava special extract WS 1490 in general practice: a randomized placebo-controlled double-blind multicenter trialPhytomedicine.(2003 Nov)
    17. Anxiety Symptoms - Pittler MH, Ernst EKava extract for treating anxietyCochrane Database Syst Rev.(2003)
    18. Anxiety Symptoms - Zhang W, Yan Y, Wu Y, Yang H, Zhu P, Yan F, Zhao R, Tian P, Wang T, Fan Q, Su ZMedicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.Pharmacol Res.(2022-May)
    19. Anxiety Symptoms - Pittler MH, Ernst EEfficacy of kava extract for treating anxiety: systematic review and meta-analysis.J Clin Psychopharmacol.(2000-Feb)
    20. Anxiety Symptoms - Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Dienel A, Schläfke SSilexan, an orally administered Lavandula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder: a randomized, double-blind, placebo controlled trialInt Clin Psychopharmacol.(2010 Sep)
    21. Anxiety Symptoms - Yap WS, Dolzhenko AV, Jalal Z, Hadi MA, Khan TMEfficacy and safety of lavender essential oil (Silexan) capsules among patients suffering from anxiety disorders: A network meta-analysisSci Rep.(2019 Dec 2)
    22. Anxiety Symptoms - Dold M, Bartova L, Volz HP, Seifritz E, Möller HJ, Schläfke S, Kasper SEfficacy of Silexan in patients with anxiety disorders: a meta-analysis of randomized, placebo-controlled trials.Eur Arch Psychiatry Clin Neurosci.(2023-Jan-30)
    23. Anxiety Symptoms - Möller HJ, Volz HP, Dienel A, Schläfke S, Kasper SEfficacy of Silexan in subthreshold anxiety: meta-analysis of randomised, placebo-controlled trials.Eur Arch Psychiatry Clin Neurosci.(2019-Mar)
    24. Anxiety Symptoms - Kang HJ, Nam ES, Lee Y, Kim MHow Strong is the Evidence for the Anxiolytic Efficacy of Lavender?: Systematic Review and Meta-analysis of Randomized Controlled Trials.Asian Nurs Res (Korean Soc Nurs Sci).(2019-Dec)
    25. Fatigue Symptoms - Roland von Känel, Siegfried Kasper, Guido Bondolfi, Edith Holsboer-Trachsler, Josef Hättenschwiler, Martin Hatzinger, Christian Imboden, Ellen Heitlinger, Erich SeifritzTherapeutic effects of Silexan on somatic symptoms and physical health in patients with anxiety disorders: A meta-analysisBrain Behav.(2021 Feb 27)
    26. Anxiety Symptoms - Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SGPilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbancesMed J Nutrition Metab.(2011 Dec)
    27. Anxiety Symptoms - Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki KReduction of depression and anxiety by 4 weeks Hericium erinaceus intakeBiomed Res.(2010 Aug)
    28. Anxiety Symptoms - Tomohiko Mukai, Taro Kishi, Yuki Matsuda, Nakao IwataA meta-analysis of inositol for depression and anxiety disordersHum Psychopharmacol.(2014 Jan)
    29. Depression Symptoms - Ross SMRhodiola rosea (SHR-5), Part I: a proprietary root extract of Rhodiola rosea is found to be effective in the treatment of stress-related fatigueHolist Nurs Pract.(2014 Mar-Apr)