Dietary supplements have not been formally studied for EDS. However, supplements may be recommended to correct nutritional deficiencies linked with EDS and to manage symptoms. For example, hEDS has been linked with low vitamin D levels, so supplementation with vitamin D is often recommended. Anecdotally, vitamin C has been tried to improve wound healing and skin fragility, glucosamine for joint pain, and carnitine and coenzyme Q10 for fatigue and muscle weakness.