Fatigue

    Researchedby:
    Nick Milazzo
    Last Updated: October 13, 2024

    Fatigue refers to a feeling of tiredness that does not improve with sleep or rest. It can be due to intense and/or prolonged physical and mental activity or due to other causes not related to exertion (e.g., anxiety/depression, medications, disease, pregnancy).

    Fatigue falls under the Energy & Fatigue category.

    2,752 participants in 16 trials and 4 meta-analyses

    Examine Database: Fatigue

    Research FeedRead all studies

    Examine Database References

    1. Fatigue Symptoms - Li Zhang, Xiaoyun Chen, Yanqi Cheng, Qilong Chen, Hongsheng Tan, Dongwook Son, Dongpill Chang, Zhaoxiang Bian, Hong Fang, Hongxi XuSafety and antifatigue effect of Korean Red Ginseng: a randomized, double-blind, and placebo-controlled clinical trialJ Ginseng Res.(2019 Oct)
    2. Fatigue Symptoms - Namhun Lee, Suk-Hoon Lee, Ho-Ryong Yoo, Hwa Seung YooAnti-Fatigue Effects of Enzyme-Modified Ginseng Extract: A Randomized, Double-Blind, Placebo-Controlled TrialJ Altern Complement Med.(2016 Nov)
    3. Fatigue Symptoms - Tahereh Fathi Najafia, Narjes Bahrib, Hamid Reza Tohidinik, Sahar Feyza, Farnaz Blokia, Safora Savarkar, Shayesteh JahanfarTreatment of cancer-related fatigue with ginseng: A systematic review and meta-analysisJournal of Herbal Medicine.()
    4. Fatigue Symptoms - Portier H, Chatard JC, Filaire E, Jaunet-Devienne MF, Robert A, Guezennec CYEffects of branched-chain amino acids supplementation on physiological and psychological performance during an offshore sailing raceEur J Appl Physiol.(2008 Nov)
    5. Fatigue Symptoms - Kokubo T, Ikeshima E, Kirisako T, Miura Y, Horiuchi M, Tsuda AA randomized, double-masked, placebo-controlled crossover trial on the effects of L-ornithine on salivary cortisol and feelings of fatigue of flushers the morning after alcohol consumptionBiopsychosoc Med.(2013 Feb 18)
    6. Fatigue Symptoms - Sugino T, Shirai T, Kajimoto Y, Kajimoto OL-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolismNutr Res.(2008 Nov)
    7. Fatigue Symptoms - Punja S, Shamseer L, Olson K, Vohra SRhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trialPLoS One.(2014 Sep 30)
    8. Fatigue Symptoms - Schutgens FW, Neogi P, van Wijk EP, van Wijk R, Wikman G, Wiegant FAThe influence of adaptogens on ultraweak biophoton emission: a pilot-experimentPhytother Res.(2009 Aug)
    9. Fatigue Symptoms - Salima Punja, Larissa Shamseer, Karin Olson, Sunita VohraRhodiola Rosea for Mental and Physical Fatigue in Nursing Students: A Randomized Controlled TrialPLoS.()
    10. Depression Symptoms - Olsson EM, von Schéele B, Panossian AGA randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatiguePlanta Med.(2009 Feb)
    11. Fatigue Symptoms - Stout JR, Graves BS, Smith AE, Hartman MJ, Cramer JT, Beck TW, Harris RCThe effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55-92 Years): a double-blind randomized studyJ Int Soc Sports Nutr.(2008 Nov 7)
    12. Fatigue Symptoms - Malaguarnera M, Gargante MP, Cristaldi E, Colonna V, Messano M, Koverech A, Neri S, Vacante M, Cammalleri L, Motta MAcetyl L-carnitine (ALC) treatment in elderly patients with fatigueArch Gerontol Geriatr.(2008 Mar-Apr)
    13. Fatigue Symptoms - Masahiko Nakano, Tetsuro Yamamoto, Hisayoshi Okamura, Akira Tsuda, Yasuyuki KowatariEffects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and SleepFunctional Foods in Health and Disease.()
    14. Fatigue Symptoms - I-Chen Tsai, Chih-Wei Hsu, Chun-Hung Chang, Ping-Tao Tseng, Ke-Vin ChangEffectiveness of Coenzyme Q10 Supplementation for Reducing Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsFront Pharmacol.(2022 Aug 24)
    15. Fatigue Symptoms - Park BJ, Choi Y, Lee JS, Ahn YC, Lee EJ, Son CGEffectiveness of meditation for fatigue management: Insight from a comprehensive systematic review and meta-analysis.Gen Hosp Psychiatry.(2024 Aug 11)
    16. Exercise Capacity - Houston BL, Hurrie D, Graham J, Perija B, Rimmer E, Rabbani R, Bernstein CN, Turgeon AF, Fergusson DA, Houston DS, Abou-Setta AM, Zarychanski REfficacy of iron supplementation on fatigue and physical capacity in non-anaemic iron-deficient adults: a systematic review of randomised controlled trialsBMJ Open.(2018 Apr 5)
    17. Anxiety Symptoms - Vaucher P, Druais PL, Waldvogel S, Favrat BEffect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trialCMAJ.(2012 Aug 7)
    18. Aerobic Exercise Metrics - Ataka S, Tanaka M, Nozaki S, Mizuma H, Mizuno K, Tahara T, Sugino T, Shirai T, Kajimoto Y, Kuratsune H, Kajimoto O, Watanabe YEffects of Applephenon and ascorbic acid on physical fatigueNutrition.(2007 May)
    19. Aerobic Exercise Metrics - Morgan Johnson, Lauren Hassinger, Joshua Davis, Steven T Devor, Robert A DiSilvestroA randomized, double blind, placebo controlled study of spirulina supplementation on indices of mental and physical fatigue in menInt J Food Sci Nutr.(2016)
    20. Cognitive Function - Talik TN, Penna EM, Hack BP, Harp A, Millard-Stafford MEffects of Acute Guarana (Paullinia cupana) Ingestion on Mental Performance and Vagal Modulation Compared to a Low Dose of Caffeine.Nutrients.(2024 Jun 15)