Have any supplements been studied for heart failure?

    Last Updated: October 25, 2023

    Some supplements studied for heart failure include coenzyme Q10, vitamin D, iron, L-carnitine, thiamine, and other B vitamins. For most supplements, evidence of benefit is very limited. However, for coenzyme Q10, a meta-analysis of 7 clinical studies in about 1800 participants with heart failure found that it may slightly reduce the risk of mortality compared to control.[1] In contrast, taking vitamin E has been linked with increased heart failure hospitalizations compared to control.[2]

    References

    1. ^Khan MS, Khan F, Fonarow GC, Sreenivasan J, Greene SJ, Khan SU, Usman MS, Vaduganathan M, Fudim M, Anker SD, Butler JDietary interventions and nutritional supplements for heart failure: a systematic appraisal and evidence map.Eur J Heart Fail.(2021-Sep)
    2. ^Aggarwal M, Bozkurt B, Panjrath G, Aggarwal B, Ostfeld RJ, Barnard ND, Gaggin H, Freeman AM, Allen K, Madan S, Massera D, Litwin SE,Lifestyle Modifications for Preventing and Treating Heart Failure.J Am Coll Cardiol.(2018-Nov-06)