Evidence-based
Major Depressive Disorder (MDD)
Written by:
•Last Updated: November 20, 2025
MDD, otherwise known as clinical depression or major depression, is a more severe form of depression that may involve feelings of sadness, angry outbursts, a loss of interest in everyday activities, fatigue, feelings of worthlessness, difficulty thinking, and thoughts of suicide.
Major Depressive Disorder (MDD) falls under the Mental Health category.
