Stress

    Researchedby:
    Nick Milazzo
    Last Updated: October 13, 2024

    Stress (particularly distress) is excessive stimulation of the body's resources that eventually leads to negative symptoms such as fatigue or depression. Several supplements, such as adaptogens, are thought to reduce the development of stress.

    examine-databaseExamine Database

    Stress falls under the Mental Health category.

    2,641 participants in 25 trials and 3 meta-analyses

    Examine Database: Stress

    Ashwagandha
    Theanine
    L-Tyrosine
    Rhodiola Rosea
    Alcohol
    Bacopa Monnieri
    Binaural Beats
    Cannabidiol (CBD)
    Cocoa Extract
    Dietary Approaches to Stop Hypertension (DASH) Diet
    Kanna
    Kava
    Lemon Balm
    Magnesium
    Melatonin
    PQQ
    Patchouli
    Phosphatidylserine
    Probiotics
    Saffron

    Research FeedRead all studies

    Examine Database References

    1. Anxiety Symptoms - Zuardi AW, Rodrigues NP, Silva AL, Bernardo SA, Hallak JEC, Guimarães FS, Crippa JASInverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real LifeFront Pharmacol.(2017 May 11)
    2. Anxiety Symptoms - Kimura K, Ozeki M, Juneja LR, Ohira HL-Theanine reduces psychological and physiological stress responsesBiol Psychol.(2007 Jan)
    3. Anxiety Symptoms - Shinsuke Hidese, Shintaro Ogawa, Miho Ota, Ikki Ishida, Zenta Yasukawa, Makoto Ozeki, Hiroshi KunugiEffects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled TrialNutrients.(2019 Oct 3)
    4. Anxiety Symptoms - Williams JL, Everett JM, D'Cunha NM, Sergi D, Georgousopoulou EN, Keegan RJ, McKune AJ, Mellor DD, Anstice N, Naumovski NThe Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review.Plant Foods Hum Nutr.(2020-Mar)
    5. Stress Signs and Symptoms - Moulin M, Crowley DC, Xiong L, Guthrie N, Lewis EDSafety and Efficacy of AlphaWave(®) L-Theanine Supplementation for 28 Days in Healthy Adults with Moderate Stress: A Randomized, Double-Blind, Placebo-Controlled Trial.Neurol Ther.(2024 Aug)
    6. Anxiety Symptoms - Graham Kell, Amanda Rao, Gavin Beccaria, Paul Clayton, Antonio Manuel Inarejos-García, Marin Prodanovaffron ® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trialComplement Ther Med.(2017 Aug)
    7. Anxiety Symptoms - Dimpfel W, Pischel I, Lehnfeld REffects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volunteersEur J Med Res.(2004 Sep 29)
    8. Anxiety Symptoms - Rimmele U, Spillmann M, Bärtschi C, Wolf OT, Weber CS, Ehlert U, Wirtz PHMelatonin improves memory acquisition under stress independent of stress hormone releasePsychopharmacology (Berl).(2009 Mar)
    9. Anxiety Symptoms - Terburg D, Syal S, Rosenberger LA, Heany S, Phillips N, Gericke N, Stein DJ, van Honk JAcute effects of Sceletium tortuosum (Zembrin), a dual 5-HT reuptake and PDE4 inhibitor, in the human amygdala and its connection to the hypothalamusNeuropsychopharmacology.(2013 Dec)
    10. Anxiety Symptoms - Auddy, B, et alA Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled StudyJ Am Nut Assn.()
    11. Anxiety Symptoms - Camellia Akhgarjand, Farzaneh Asoudeh, Amir Bagheri, Zahra Kalantar, Zahra Vahabi, Sakineh Shab-Bidar, Hamid Rezvani, Kurosh DjafarianDoes Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trialsPhytother Res.(2022 Aug 25)
    12. Heart Rate - Choudhary D, Bhattacharyya S, Joshi KBody Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled TrialJ Evid Based Complementary Altern Med.(2017 Jan)
    13. Stress Signs and Symptoms - .(2024-04-26)
    14. CNS activity - Haze S, Sakai K, Gozu YEffects of fragrance inhalation on sympathetic activity in normal adultsJpn J Pharmacol.(2002 Nov)
    15. Heart Rate - Harris R Lieberman, Lauren A Thompson, Christina M Caruso, Philip J Niro, Caroline R Mahoney, James P McClung, Gregory R CaronThe catecholamine neurotransmitter precursor tyrosine increases anger during exposure to severe psychological stressPsychopharmacology (Berl).(2015 Mar)
    16. Heart Rate - Banderet LE, Lieberman HRTreatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humansBrain Res Bull.(1989 Apr)
    17. Stress Signs and Symptoms - Katherine Kelton, Terri L Weaver, Lisa Willoughby, David Kaufman, Anna SantowskiThe Efficacy of Binaural Beats as a Stress-buffering TechniqueAltern Ther Health Med.(2020 Jul 1)
    18. Stress Signs and Symptoms - D WheatleyKava and valerian in the treatment of stress-induced insomniaPhytother Res.(2001 Sep)
    19. Stress Signs and Symptoms - D Edwards, A Heufelder, A ZimmermannTherapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms--results of an open-label studyPhytother Res.(2012 Aug)
    20. Cortisol - Olsson EM, von Schéele B, Panossian AGA randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatiguePlanta Med.(2009 Feb)
    21. Stress Signs and Symptoms - Sarah Benson, Luke A Downey, Con Stough, Mark Wetherell, Andrea Zangara, Andrew ScholeyAn acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and moodPhytother Res.(2014 Apr)
    22. Stress Signs and Symptoms - Masahiko Nakano, Tetsuro Yamamoto, Hisayoshi Okamura, Akira Tsuda, Yasuyuki KowatariEffects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and SleepFunctional Foods in Health and Disease.()
    23. Stress Signs and Symptoms - Noah L, Dye L, Bois De Fer B, Mazur A, Pickering G, Pouteau EEffect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial.Stress Health.(2021-Dec)
    24. Blood Lactate (Exercise) - Monteleone P, Maj M, Beinat L, Natale M, Kemali DBlunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy menEur J Clin Pharmacol.(1992)
    25. Cortisol - Välimäki MJ, Härkönen M, Eriksson CJ, Ylikahri RHSex hormones and adrenocortical steroids in men acutely intoxicated with ethanolAlcohol.(1984 Jan-Feb)
    26. Sleep Quality - .(2024-05-30)
    27. Noradrenaline - von Känel R, Meister RE, Stutz M, Kummer P, Arpagaus A, Huber S, Ehlert U, Wirtz PHEffects of dark chocolate consumption on the prothrombotic response to acute psychosocial stress in healthy menThromb Haemost.(2014 Dec)
    28. Total Antioxidant Capacity (TAC) - Pirouzeh R, Heidarzadeh-Esfahani N, Morvaridzadeh M, Izadi A, Yosaee S, Potter E, Heshmati J, Pizarro AB, Omidi A, Heshmati SEffect of DASH diet on oxidative stress parameters: A systematic review and meta-analysis of randomized clinical trials.Diabetes Metab Syndr.(2020 Nov-Dec)