Vitamin D has been shown to reduce inflammatory biomarkers related to UC and improve intestinal barrier function when used as an adjunctive treatment to 5-ASA medications.[1] Curcumin may also help achieve remission, but more robust studies are needed.[2]
There is some evidence to support the use of probiotics, prebiotics, and synbiotics (a supplement containing both probiotics and prebiotics) in achieving remission and lowering inflammatory biomarkers related to UC.[3][4]
Since people with IBD are susceptible to nutritional deficiencies, the European Society for Clinical Nutrition and Metabolism recommends supplementation with nutrients such as iron, vitamin D, and folic acid in those who are deficient.[5]