Yerba mate is usually consumed as a beverage. It is prepared by infusing hot or cold water with dried (referred to as “green”) or roasted yerba mate leaves or by dissolving instant yerba mate tea in water. Yerba mate can also be taken as a capsule containing powdered yerba mate leaves or dehydrated tea extract.

Yerba mate tea infusions are typically consumed in volumes of around 1 liter (1,000 mL, around 4 cups) daily, divided into three doses. This is the dosage form used in studies that have reported reductions in LDL cholesterol in dyslipidemia and improved glucose parameters in people with type 2 diabetes.

Instant yerba mate tea has been used at dosages ranging from 2.5 to 5 grams daily, divided into three doses.

Dosages of yerba mate capsules usually range from 1.5 to 3 grams daily, divided into three doses. This is the dosage form most studied for increasing fat oxidation and reducing body fat.

All of the formulations have demonstrated antioxidant effects.