Examine Database: Risk Of Cardiovascular Disease
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Vitamin D | D | ||
| Curcumin | B | ||
| Mediterranean Diet | B | ||
| Vitamin E | |||
| Cocoa Extract | |||
| Honey | |||
| Elderberry |
Research FeedRead all studies
Supplementing with vitamin D doesn’t improve cardiovascular disease risk
In this meta-analysis of 5 randomized controlled trials in 57,201 participants, vitamin D did not affect the risk of major adverse cardiovascular events or cardiovascular disease mortality.
Extra-virgin olive oil may support cardiometabolic health
E-cigarettes aren’t harmless, and combining them with cigarettes makes them even worse
Associations between coffee and tea intake and mortality in participants with diabetes
Omega-6 fatty acids and mortality risks
Examine Database References
- Vitamin D - Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz WIndependent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortalityArch Intern Med.(2008 Jun 23)
- Vitamin D - Wang L, Manson JE, Song Y, Sesso HDSystematic review: Vitamin D and calcium supplementation in prevention of cardiovascular eventsAnn Intern Med.(2010 Mar 2)
- Vitamin D - Seibert E, Lehmann U, Riedel A, Ulrich C, Hirche F, Brandsch C, Dierkes J, Girndt M, Stangl GIVitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D statusEur J Nutr.(2015 Nov 30)
- Vitamin E - Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JEVitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trialJAMA.(2005 Jul 6)
- Elderberry - Curtis PJ, Kroon PA, Hollands WJ, Walls R, Jenkins G, Kay CD, Cassidy ACardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks.J Nutr.(2009-Dec)
- Mediterranean Diet - Becerra-Tomás N, Blanco Mejía S, Viguiliouk E, Khan T, Kendall CWC, Kahleova H, Rahelić D, Sievenpiper JL, Salas-Salvadó JMediterranean diet, cardiovascular disease and mortality in diabetes: A systematic review and meta-analysis of prospective cohort studies and randomized clinical trials.Crit Rev Food Sci Nutr.(Jan 24 2019)
- Honey - Semnani-Azad Z, Khan TA, Blanco Mejia S, de Souza RJ, Leiter LA, Kendall CWC, Hanley AJ, Sievenpiper JLAssociation of Major Food Sources of Fructose-Containing Sugars With Incident Metabolic Syndrome: A Systematic Review and Meta-analysis.JAMA Netw Open.(2020 Jul 1)
- Cocoa Extract - Buitrago-Lopez A, Sanderson J, Johnson L, Warnakula S, Wood A, Di Angelantonio E, Franco OHChocolate consumption and cardiometabolic disorders: systematic review and meta-analysis.BMJ.(2011 Aug 26)
- Curcumin - Fogacci F, Avagimyan A, Cesaro A, Bernardi M, Perone F, Giovannini M, Cicero AFGThe effect of highly bioavailable forms of curcumin on lipoprotein(a) plasma levels: A systematic review and meta-analysis of randomized clinical studies.Prostaglandins Other Lipid Mediat.(2025 Jun)
- Vitamin D - Cheng X, Chen Z, Fang Y, Zhang Q, Chen B, Xi W, Pan Z, Guo LEffect of vitamin D supplementation for major adverse cardiovascular events: a meta-analysis based on randomised controlled trials.Br J Nutr.(2025 Jul 21)