Examine Database: All-Cause Mortality
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Does when you drink coffee influence its health benefits?
In this cohort study in 42,188 participants, drinking caffeinated or decaffeinated coffee in the morning was associated with a lower risk of cardiovascular disease (CVD) mortality and all-cause mortality. Drinking coffee all day did not have protective associations.
The association between artificial sweeteners and the risk of cardiovascular events
Higher olive oil consumption is linked to a lower mortality risk
Supplemental vitamin D and health outcomes in people with COVID-19
Following a Mediterranean diet may help older adults live longer and healthier
Examine Database References
- Vitamin E - Lee IM, Cook NR, Gaziano JM, Gordon D, Ridker PM, Manson JE, Hennekens CH, Buring JEVitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study: a randomized controlled trialJAMA.(2005 Jul 6)
- Vitamin E - McNeil JJ, Robman L, Tikellis G, Sinclair MI, McCarty CA, Taylor HRVitamin E supplementation and cataract: randomized controlled trialOphthalmology.(2004 Jan)
- Vitamin E - Miller ER 3rd, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar EMeta-analysis: high-dosage vitamin E supplementation may increase all-cause mortalityAnn Intern Med.(2005 Jan 4)
- Vitamin D - Bjelakovic G, Gluud LL, Nikolova D, Whitfield K, Wetterslev J, Simonetti RG, Bjelakovic M, Gluud CVitamin D supplementation for prevention of mortality in adultsCochrane Database Syst Rev.(2011 Jul 6)
- Vitamin E - Meydani SN, Leka LS, Fine BC, Dallal GE, Keusch GT, Singh MF, Hamer DHVitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trialJAMA.(2004 Aug 18)
- Vitamin D - Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz WIndependent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortalityArch Intern Med.(2008 Jun 23)
- Vitamin E - Buring JEAspirin prevents stroke but not MI in women; vitamin E has no effect on CV disease or cancerCleve Clin J Med.(2006 Sep)
- Vitamin E - Lonn E, Bosch J, Yusuf S, Sheridan P, Pogue J, Arnold JM, Ross C, Arnold A, Sleight P, Probstfield J, Dagenais GR, HOPE and HOPE-TOO Trial InvestigatorsEffects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trialJAMA.(2005 Mar 16)
- N-Acetylcysteine - Pereira JEG, El Dib R, Braz LG, Escudero J, Hayes J, Johnston BCN-acetylcysteine use among patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized trials.PLoS One.(2019 May 9)
- N-Acetylcysteine - Rogliani P, Calzetta L, Cavalli F, Matera MG, Cazzola MPirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis.Pulm Pharmacol Ther.(2016-Oct)
- Fish Oil - Wu G, Ji Q, Huang H, Zhu XThe efficacy of fish oil in preventing coronary heart disease: A systematic review and meta-analysis.Medicine (Baltimore).(2021-Sep-17)
- Fish Oil - Yu F, Qi S, Ji Y, Wang X, Fang S, Cao REffects of omega-3 fatty acid on major cardiovascular outcomes: A systematic review and meta-analysis.Medicine (Baltimore).(2022-Jul-29)
- Alpha-Linolenic Acid (ALA) - Asmaa S Abdelhamid, Tracey J Brown, Julii S Brainard, Priti Biswas, Gabrielle C Thorpe, Helen J Moore, Katherine Ho Deane, Carolyn D Summerbell, Helen V Worthington, Fujian Song, Lee HooperOmega-3 fatty acids for the primary and secondary prevention of cardiovascular diseaseCochrane Database Syst Rev.(2020 Feb 29)
- Iron - Mei Z, Chen J, Luo S, Jin L, Liu Q, Chen YComparative efficacy of intravenous and oral iron supplements for the treatment of iron deficiency in patients with heart failure: A network meta-analysis of randomized controlled trials.Pharmacol Res.(2022-Aug)
- Iron - Hamza M, Sattar Y, Manasrah N, Patel NN, Rashdi A, Khanal R, Naveed H, Zafar M, Khan AM, Alharbi A, Aamir M, Gonuguntla K, Raina S, Balla SMeta-Analysis of Efficacy and Safety of Intravenous Iron in Patients With Iron Deficiency and Heart Failure With Reduced Ejection Fraction.Am J Cardiol.(2023-Sep-01)
- Mediterranean Diet - Liyanage T, Ninomiya T, Wang A, Neal B, Jun M, Wong MG, Jardine M, Hillis GS, Perkovic VEffects of the Mediterranean Diet on Cardiovascular Outcomes-A Systematic Review and Meta-AnalysisPLoS One.(2016 Aug 10)
- Mediterranean Diet - Karam G, Agarwal A, Sadeghirad B, Jalink M, Hitchcock CL, Ge L, Kiflen R, Ahmed W, Zea AM, Milenkovic J, Chedrawe MA, Rabassa M, El Dib R, Goldenberg JZ, Guyatt GH, Boyce E, Johnston BCComparison of seven popular structured dietary programmes and risk of mortality and major cardiovascular events in patients at increased cardiovascular risk: systematic review and network meta-analysis.BMJ.(2023-Mar-29)
- Mediterranean Diet - Chen G, Leary S, Niu J, Perry R, Papadaki AThe Role of the Mediterranean Diet in Breast Cancer Survivorship: A Systematic Review and Meta-Analysis of Observational Studies and Randomised Controlled Trials.Nutrients.(2023-Apr-27)
- Red Yeast Rice - Yuan R, Yuan Y, Wang L, Xin Q, Wang Y, Shi W, Miao Y, Leng SX, Chen K, Cong W,Red Yeast Rice Preparations Reduce Mortality, Major Cardiovascular Adverse Events, and Risk Factors for Metabolic Syndrome: A Systematic Review and Meta-analysis.Front Pharmacol.(2022)
- DHEA - van der Burgh AC, Khan SR, Neggers SJCMM, Hoorn EJ, Chaker LThe role of serum testosterone and dehydroepiandrosterone sulfate in kidney function and clinical outcomes in chronic kidney disease: a systematic review and meta-analysis.Endocr Connect.(2022-Jun-01)
- Vitamin C - Sharma Y, Sumanadasa S, Shahi R, Woodman R, Mangoni AA, Bihari S, Thompson CEfficacy and safety of vitamin C supplementation in the treatment of community-acquired pneumonia: a systematic review and meta-analysis with trial sequential analysis.Sci Rep.(2024 May 24)
- N-Acetylcysteine - Orban C, Agapie M, Bratu A, Jafal M, Duțu M, Popescu MNo Significant Beneficial Effects of Intravenous N-Acetylcysteine on Patient Outcome in Non-Paracetamol Acute Liver Failure: A Meta-Analysis of Randomized Controlled Trials.Biomedicines.(2024 Jul 1)
- Glutamine - Jiang W, Shi K, Shao J, Song L, Shi Y, Wang H, Zhou L, Li L, Feng Y, Yu J, Zheng RProtective effect of intravenous amino acid on kidney function: A systematic review and meta-analysis of randomized controlled trials.J Crit Care.(2024 Oct 23)
- Low-Protein Diet - Chen CH, Tsai PH, Tsai WC, Ko MJ, Hsu LY, Chien KL, Hung KY, Wu HYEfficacy and safety of ketoanalogue supplementation combined with protein-restricted diets in advanced chronic kidney disease: a systematic review and meta-analysis.J Nephrol.(2024 Sep 28)
- Probiotics - McDougall A, Nguyen R, Nguyen PY, Allen C, Cheang S, Makama M, Mills K, Hastie R, Ammerdorffer A, Gulmezoglu AM, Vogel JPThe effects of probiotics administration during pregnancy on preeclampsia and associated maternal, fetal, and newborn outcomes: a systematic review and meta-analysis.Am J Obstet Gynecol MFM.(2024 Mar 4)
- Vitamin D - Mirza AMW, Almansouri NE, Muslim MF, Basheer T, Uppalapati SV, Lakra S, Fatima H, Adhnon A, Filho IW, Mahmood R, Kumar M, Kandel K, Ayyan MEffect of vitamin D supplementation on cardiovascular outcomes: an updated meta-analysis of RCTs.Ann Med Surg (Lond).(2024 Aug 14)
- Vitamin D - Sartini M, Del Puente F, Carbone A, Schinca E, Ottria G, Dupont C, Piccinini C, Oliva M, Cristina MLThe Effect of Vitamin D Supplementation Post COVID-19 Infection and Related Outcomes: A Systematic Review and Meta-Analysis.Nutrients.(2024 Nov 5)
- Cocoa Extract - Morze J, Schwedhelm C, Bencic A, Hoffmann G, Boeing H, Przybylowicz K, Schwingshackl LChocolate and risk of chronic disease: a systematic review and dose-response meta-analysis.Eur J Nutr.(2020-Feb)
- Cocoa Extract - Zhao B, Gan L, Yu K, Männistö S, Huang J, Albanes DRelationship between chocolate consumption and overall and cause-specific mortality, systematic review and updated meta-analysis.Eur J Epidemiol.(2022 Apr)
- Fish Oil - Safi U Khan, Ahmad N Lone, Muhammad Shahzeb Khan, Salim S Virani, Roger S Blumenthal, Khurram Nasir, Michael Miller, Erin D Michos, Christie M Ballantyne, William E Boden, Deepak L BhattEffect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysisEClinicalMedicine.(2021 Jul 8)