Examine Database: Liver Fibrosis
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Mediterranean Diet | D | ||
| Betaine | B | ||
| Curcumin | C | ||
| Vitamin E | |||
| Ketogenic Diet | |||
| Synbiotics | |||
| Cordyceps | |||
| Citrulline | |||
| S-adenosylmethionine |
Research FeedRead all studies
Can silymarin improve liver function in chronic liver disease?
In this 12-week nonrandomized controlled trial in 141 men and women with chronic liver disease, silymarin reduced (improved) the liver enzymes ALT (–33% vs. –19%) and AST (–34% vs. –27%), compared with the control.
Clearing the gut to ease the liver: Can Helicobacter pylori eradication help with fatty liver disease?
Does eating quinoa at lunch improve cardiometabolic risk factors?
Does combining calorie restriction with time-restricted eating provide additional benefits with NAFLD?
Combining a lacto-ovo vegetarian diet with time-restricted eating for nonalcoholic fatty liver disease
Examine Database References
- Betaine - Sandeep Mukherjee, Tamara Bernard, Kusum Kharbanda, Anthony J. Barak, Michael F. Sorrell, Dean J. TumaImpact of Betaine on Hepatic Fibrosis and Homocysteine in Nonalcoholic Steatohepatitis - A Prospective, Cohort StudyThe Open Translational Medicine Journal.()
- Ketogenic Diet - Athinarayanan SJ, Adams RN, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, Volek JS, Phinney SD, McCarter JPLong-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical TrialFront Endocrinol (Lausanne).(2019 Jun 5)
- Citrulline - Zahra Darabi, Mina Darand, Zahra Yari, Mehdi Hedayati, Amirhosein Faghihi, Shahram Agah, Azita HekmatdoostInflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trialBMC Res Notes.(2019 Feb 15)
- Curcumin - Rahmani S, Asgary S, Askari G, Keshvari M, Hatamipour M, Feizi A, Sahebkar ATreatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled TrialPhytother Res.(2016 Sep)
- S-adenosylmethionine - Medici V, Virata MC, Peerson JM, Stabler SP, French SW, Gregory JF 3rd, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Richards JR, Halsted CHS-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trialAlcohol Clin Exp Res.(2011 Nov)
- Vitamin E - T Hasegawa, M Yoneda, K Nakamura, I Makino, A TeranoPlasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot studyAliment Pharmacol Ther.(2001 Oct)
- Betaine - Abdelmalek MF, Angulo P, Jorgensen RA, Sylvestre PB, Lindor KDBetaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot studyAm J Gastroenterol.(2001 Sep)
- Curcumin - Saeede Saadati, Behzad Hatami, Zahra Yari, Mohammad Amin Shahrbaf, Sareh Eghtesad, Asieh Mansour, Hossein Poustchi, Mehdi Hedayati, Morteza Aghajanpoor-Pasha, Amir Sadeghi, Azita HekmatdoostThe effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver diseaseEur J Clin Nutr.(2019 Mar)
- Betaine - Abdelmalek MF, Sanderson SO, Angulo P, Soldevila-Pico C, Liu C, Peter J, Keach J, Cave M, Chen T, McClain CJ, Lindor KDBetaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trialHepatology.(2009 Dec)
- Cordyceps - Li Y, Xue WJ, Tian PX, Ding XM, Yan H, Pan XM, Feng XSClinical application of Cordyceps sinensis on immunosuppressive therapy in renal transplantationTransplant Proc.(2009 Jun)
- Mediterranean Diet - Haigh L, Kirk C, El Gendy K, Gallacher J, Errington L, Mathers JC, Anstee QMThe effectiveness and acceptability of Mediterranean diet and calorie restriction in non-alcoholic fatty liver disease (NAFLD): A systematic review and meta-analysis.Clin Nutr.(2022-Sep)
- Mediterranean Diet - Del Bo' C, Perna S, Allehdan S, Rafique A, Saad S, AlGhareeb F, Rondanelli M, Tayyem RF, Marino M, Martini D, Riso PDoes the Mediterranean Diet Have Any Effect on Lipid Profile, Central Obesity and Liver Enzymes in Non-Alcoholic Fatty Liver Disease (NAFLD) Subjects? A Systematic Review and Meta-Analysis of Randomized Control Trials.Nutrients.(2023-May-09)
- Vitamin E - Chee NM, Sinnanaidu RP, Chan WKVitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.J Gastroenterol Hepatol.(2024 Aug 16)
- Synbiotics - Musazadeh V, Assadian K, Rajabi F, Faghfouri AH, Soleymani Y, Kavyani Z, Najafiyan BThe effect of synbiotics on liver enzymes, obesity indices, blood pressure, lipid profile, and inflammation in patients with non-alcoholic fatty liver: A systematic review and meta-analysis of randomized controlled trials.Pharmacol Res.(2024 Sep 4)