Examine Database: Walking Ability
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| L-Carnitine | D | ||
| Nicotinamide Mononucleotide | D | ||
| Cannabis | C | ||
| Medium-chain Triglycerides | |||
| Vitamin D | |||
| Melatonin | |||
| Fish Oil | |||
| Sauna |
Research FeedRead all studies
Can supplementation with NMN and NR rejuvenate aging muscles?
In this systematic review and meta-analysis of 10 randomized controlled trials, supplementation with nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) generally did not improve measures of muscle strength or physical function in older adults.
Oral nutritional supplements for older adults
Could melatonin improve balance and walking ability in people with multiple sclerosis?
Yoga and hot/cold compresses for spinal cord injury rehabilitation
Nutritional interventions may improve strength and body composition in older adults
Examine Database References
- Vitamin D - Soma Saha, Ravinder Goswami, Lakshmy Ramakrishnan, Sreenivas Vishnubhatla, Samrina Mahtab, Parmita Kar, Sunita Srinivasan, Namrata Singh, Upinderpal SinghVitamin D and calcium supplementation, skeletal muscle strength and serum testosterone in young healthy adult males: Randomized control trialClin Endocrinol (Oxf).(2018 Feb)
- L-Carnitine - G A Barker, S Green, C D Askew, A A Green, P J WalkerEffect of propionyl-L-carnitine on exercise performance in peripheral arterial diseaseMed Sci Sports Exerc.(2001 Sep)
- L-Carnitine - William R Hiatt, Mark A Creager, Antonino Amato, Eric P BrassEffect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery diseaseJ Cardiopulm Rehabil Prev.(Mar-Apr 2011)
- L-Carnitine - G Brevetti, S Perna, C Sabbà, A Rossini, V Scotto di Uccio, E Berardi, L GodiSuperiority of L-propionylcarnitine vs L-carnitine in improving walking capacity in patients with peripheral vascular disease: an acute, intravenous, double-blind, cross-over studyEur Heart J.(1992 Feb)
- Cannabis - Letizia Leocani, Arturo Nuara, Elise Houdayer, Irene Schiavetti, Ubaldo Del Carro, Stefano Amadio, Laura Straffi, Paolo Rossi, Vittorio Martinelli, Carlos Vila, Maria Pia Sormani, Giancarlo ComiSativex(®) and clinical-neurophysiological measures of spasticity in progressive multiple sclerosisJ Neurol.(2015 Nov)
- Cannabis - Jody Corey-Bloom, Tanya Wolfson, Anthony Gamst, Shelia Jin, Thomas D Marcotte, Heather Bentley, Ben GouauxSmoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trialCMAJ.(2012 Jul 10)
- L-Carnitine - G Brevetti, M Chiariello, G Ferulano, A Policicchio, E Nevola, A Rossini, T Attisano, G Ambrosio, N Siliprandi, C AngeliniIncreases in walking distance in patients with peripheral vascular disease treated with L-carnitine: a double-blind, cross-over studyCirculation.(1988 Apr)
- Sauna - Tei C, Imamura T, Kinugawa K, Inoue T, Masuyama T, Inoue H, Noike H, Muramatsu T, Takeishi Y, Saku K, Harada K, Daida H, Kobayashi Y, Hagiwara N, Nagayama M, Momomura S, Yonezawa K, Ito H, Gojo S, Akaishi M, Miyata M, Ohishi M, Waon Therapy for Managing Chronic Heart Failure - Results From a Multicenter Prospective Randomized WAON-CHF Study.Circ J.(2016)
- Nicotinamide Mononucleotide - Yi L, Maier AB, Tao R, Lin Z, Vaidya A, Pendse S, Thasma S, Andhalkar N, Avhad G, Kumbhar VThe efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.Geroscience.(2023-Feb)
- Fish Oil - Rondanelli M, Perna S, Riva A, Petrangolini G, Di Paolo E, Gasparri CEffects of n-3 EPA and DHA supplementation on fat free mass and physical performance in elderly. A systematic review and meta-analysis of randomized clinical trial.Mech Ageing Dev.(2021-Jun)
- Melatonin - Jallouli S, Ghroubi S, Damak M, Sakka S, Elleuch MH, Mhiri C, Yahia A, Driss T, de Marco G, Hammouda O12-week melatonin supplementation improved dynamic postural stability and walking performance in persons living with multiple sclerosis: A randomized controlled trial.Behav Brain Res.(2024 Aug 8)
- Medium-chain Triglycerides - Ezaki O, Abe SMedium-chain triglycerides (8:0 and 10:0) increase muscle mass and function in frail older adults: a combined data analysis of clinical trialsFront Nutr.(2023 Dec 4)
- Medium-chain Triglycerides - Kojima K, Ishikawa H, Watanabe S, Nosaka N, Mutoh TA Randomized, Double-Blind, Controlled Trial Assessing If Medium-Chain Triglycerides in Combination with Moderate-Intensity Exercise Increase Muscle Strength in Healthy Middle-Aged and Older AdultsNutrients.(2023 Jul 24)
- Nicotinamide Mononucleotide - Prokopidis K, Moriarty F, Bahat G, McLean J, Church DD, Patel HPThe Effect of Nicotinamide Mononucleotide and Riboside on Skeletal Muscle Mass and Function: A Systematic Review and Meta-Analysis.J Cachexia Sarcopenia Muscle.(2025 Jun)