Does red yeast rice impact bone health?

    Last Updated: October 13, 2024

    There is currently a lack of evidence to suggest that RYR supplementation promotes bone health. In animal studies, RYR seems to increase the proliferation of osteoblasts (cells involved in bone formation), increase alkaline phosphatase, and increase bone mineral density.[1] However, these effects have not been validated in human clinical trials. Interestingly, observational research on statin medications suggests that statin therapy is associated with a reduced risk of fractures, but the few randomized controlled trials that have been done have generally not found an effect of statins on bone mineral density.[2]

    References

    1. ^Bin Wu, Jie-Feng Huang, Bang-Jian He, Chen-Wei Huang, Jian-Hua LuPromotion of Bone Formation by Red Yeast Rice in Experimental Animals: A Systematic Review and Meta-AnalysisBiomed Res Int.(2020 Aug 8)
    2. ^An T, Hao J, Sun S, Li R, Yang M, Cheng G, Zou MEfficacy of statins for osteoporosis: a systematic review and meta-analysis.Osteoporos Int.(2017-Jan)